Development of sodium-MRI for stroke and tumour investigations in rodents
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Andre Fagan, Friedrich Wetterling, Development of sodium-MRI for stroke and tumour investigations in rodents, IRISH JOURNAL OF MEDICAL SCIENCE, Faculty of Radiologists Royal College of Surgeons in Ireland, Dublin, 25-27 September 2008, Irish Journal of Medical Science, 177, Supplement 8, Springer, 2008, S271 - S271Download Item:
Abstract:
The aim of this research was to develop a technique for accurately
detecting and quantifying the concentration of sodium in diseased
tissue via MRI. Measures of tissue sodium concentration can pro-
vide information regarding the viability of tissue, thereby aiding in
the early detection of disease and in the development and moni-
toring of therapeutic interventions (1, 2). However, 23Na-MRI is
hindered by a signal approximately 100,000 times less than that of
conventional 1H-MRI and very short in vivo T2 relaxation times
(*1–2 ms). Consequently, it is necessary to develop specialised
hardware and imaging pulse sequence solutions to produce images
of adequate quality
Author's Homepage:
http://people.tcd.ie/wetterf
Author: Wetterling, Friedrich
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IRISH JOURNAL OF MEDICAL SCIENCEFaculty of Radiologists Royal College of Surgeons in Ireland
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177;Supplement 8;
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