Browsing Biochemistry (Theses and Dissertations) by Subject "Adjuvants"
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Modulation of macrophage responses by the vaccine adjuvant alum
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2020)Recent findings have challenged the classical view of innate versus adaptive immunity, suggesting that innate cells can retain some memory of past immunological insults. This trained immunity which allows for primed cellular ... -
Particulate adjuvants for use in cancer vaccination
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2023)It is estimated that 1 in 2 people will develop cancer in their lifetime, highlighting the urgent need for improved preventative and therapeutic strategies. Cancer immunotherapy has emerged as a key pillar of cancer ...