Browsing Mechanical & Manufacturing Eng (Scholarly Publications) by Author "Murphy, Paula"
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Dynamic patterns of mechanical stimulation co-localise with growth and cell proliferation during morphogenesis in the avian embryonic knee joint
Prendergast, Patrick; Murphy, Paula (University of Edinburgh (datashare), 2011)Muscle contractions begin in early embryonic life, generating forces that regulate the correct formation of the skeleton. In this paper we test the hypothesis that the biophysical stimulation generated by muscle forces may ... -
Mechanical Influences on Morphogenesis of the Knee Joint Revealed through Morphological, Molecular and Computational Analysis of Immobilised Embryos.
Prendergast, Patrick; Murphy, Paula (University of Edinburgh (datashare), 2011)Very little is known about the regulation of morphogenesis in synovial joints. Mechanical forces generated from muscle contractions are required for normal development of several aspects of normal skeletogenesis. Here we ...