Mechanical & Manufacturing Eng (Scholarly Publications): Recent submissions
Now showing items 121-140 of 700
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Affinity-bound growth factor within sulfated interpenetrating network bioinks for bioprinting cartilaginous tissues
(2021)3D bioprinting has emerged as a promising technology in the field of tissue engineering and regenerative medicine due to its ability to create anatomically complex tissue substitutes. However, it still remains challenging ... -
Biofabrication of Prevascularised Hypertrophic Cartilage Microtissues for Bone Tissue Engineering
(2021)Bone tissue engineering (TE) has the potential to transform the treatment of challenging musculoskeletal pathologies. To date, clinical translation of many traditional TE strategies has been impaired by poor vascularisation ... -
Measuring and Modeling Oxygen Transport and Consumption in 3D Hydrogels Containing Chondrocytes and Stem Cells of Different Tissue Origins.
(2021)Understanding how the local cellular environment influences cell metabolism, phenotype and matrix synthesis is crucial to engineering functional tissue grafts of a clinically relevant scale. The objective of this study was ... -
3D bioprinting of prevascularised implants for the repair of critically-sized bone defects
(2021)For 3D bioprinted tissues to be scaled-up to clinically relevant sizes, effective prevascularisation strategies are required to provide the necessary nutrients for normal metabolism and to remove associated waste by-products. ... -
Biofabrication and bioprinting using cellular aggregates, microtissues and organoids for the engineering of musculoskeletal tissues
(2021)The modest clinical impact of musculoskeletal tissue engineering (TE) can be attributed, at least in part, to a failure to recapitulate the structure, composition and functional properties of the target tissue. This has ... -
Hydrostatic Pressure Regulates the Volume, Aggregation and Chondrogenic Differentiation of Bone Marrow Derived Stromal Cells
(2021)The limited ability of articular cartilage to has motivated the development of tissue engineering strategies that aim to harness the regenerative potential of mesenchymal stem/marrow stromal cells (MSCs). Understanding ... -
Harnessing the innate and adaptive immune system for tissue repair and regeneration: Considering more than macrophages
(2021)Tissue healing and regeneration is a complex, choreographed, spatiotemporal process involving a plethora of cell types, the activity of which is stringently regulated in order for effective tissue repair to ensue post ... -
Using Tactile Sensing to Improve Performance when Grasping Moving Objects
(2021)To operate in unstructured settings, robots require control strategies that effectively respond to temporal changes in their environment. In the domain of robotic manipulation, most state-of-the-art approaches assume the ... -
An IoT Approach for Monitoring UV Disinfection Robots
(2021)The use of ultraviolet germicidal irradiation (UVGI) technology as a means of disinfecting hospitals and other frontline settings has increased significantly in the wake of the COVID-19 pandemic. Although the science of ... -
A Novel Linear Air Amplifier Technology to Replace Rotary Fans in Data Center Server Rack Cooling
(2020)This paper investigates the potential of a novel linear airflow amplifier designed to replace rotary fans for various industries where their performance is undesirable like electronics cooling applications in compact data ... -
Heat Transfer Characterization of a Single Source Ultra-Low Flow Rate Electrospray
(2013)The development and optimization of two phase electrospray cooling is currently restricted,in part due to the insufficient knowledge of how the various parameters that define an electrospray interact ... -
Analytical heat conduction model of annular composite fins
(2018)A two-dimensional analytical heat conduction model of an annular composite fin has been carried out.The composite fins composed of a porous polyethylene core, a square aluminum insert,and metallic zinc coating layers, ... -
Composite heat sink LED cooling
(2018)Metal coating of 3D printed polymers is an attractive proposition for thermal dissipation of light emitting diodes, due to its high efficiency and markedly lower material costs than conventional aluminum heat sinks. ... -
Plume Characterisation of a Single Source Electrospray for Micro Electronic Cooling
(2014)Development and optimization of two phase electrospray cooling is an undeveloped topic, in part due to unavailable knowledge of how the various electrical, geometrical, thermal and hydraulic parameters influence both ... -
Fabrication of Composite Heat Sinks Consisting of a Thin Metallic Skin and a Polymer Core Using Wire-Arc Spraying
(2019)Three composite heat sinks in the shape of a disk, a cylinder, and a cylinder with vertically projecting fins were made by applying a thin (0.4 – 0.7 mm) zinc layer onto ABS polymer cores using wire-arc spraying. The ... -
The effect of prior long-term recellularization with keratocytes of decellularized porcine corneas implanted in a rabbit anterior lamellar keratoplasty model.
(2021)Decellularized porcine corneal scaffolds are a potential alternative to human cornea for keratoplasty. Although clinical trials have reported promising results, there can be corneal haze or scar tissue. Here, we examined ... -
Primary cilium-mediated MSC mechanotransduction is dependent on Gpr161 regulation of hedgehog signalling.
(2021)The benefits of physical loading to skeletal mass are well known. The primary cilium has emerged as an important organelle in bone mechanobiology/mechanotransduction, particularly in mesenchymal stem/stromal cells, yet the ... -
A meta-analysis of the diagnostic accuracy of hounsfield units on computed topography relative to dual-energy X-ray absorptiometry for the diagnosis of osteoporosis in the spine surgery population.
(2021)Background: The preoperative identification of osteoporosis in the spine surgery population is of crucial importance. Limitations associated with dual-energy x-ray absorptiometry, such as access and reliability, have ... -
Estrogen withdrawal alters cytoskeletal and primary ciliary dynamics resulting in increased Hedgehog and osteoclastogenic paracrine signalling in osteocytes.
(2021)Estrogen deficiency during post-menopausal osteoporosis leads to osteoclastogenesis and bone loss. Increased pro-osteoclastogenic signalling (RANKL/OPG) by osteocytes occurs following estrogen withdrawal (EW) and is ... -
Mechanical and fatigue properties of diamond-reinforced Cu and Al metal matrix composites prepared by cold spray
(2021)Diamond-reinforced composites prepared by cold spray are emerging materials simultaneously featuring outstanding thermal conductivity and wear resistance. Their mechanical and fatigue properties relevant ...
