Mechanical & Manufacturing Eng (Scholarly Publications): Recent submissions
Now showing items 221-240 of 700
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Biomaterial-based endochondral bone regeneration: A shift from traditional tissue engineering paradigms to developmentally inspired strategies
(2019)There is an urgent, clinical need for an alternative to the use of autologous grafts for the ever increasing number of bone grafting procedures performed annually. Herein, we describe a developmentally inspired approach ... -
Glyoxal cross-linking of solubilized extracellular matrix to produce highly porous, elastic, and chondro-permissive scaffolds for orthopedic tissue engineering
(2019)Extracellular matrix (ECM)-derived implants hold great promise for tissue repair, but new strategies are required to produce efficiently decellularized scaffolds with the necessary porosity and mechanical properties to ... -
Teaching Innovation in Interdisciplinary Environments: Toward a Design Thinking Syllabus
(2018)An increasing number of universities offer user-centric innovation courses based on the principles of design thinking. Lecturers combine a plethora of design thinking elements in design thinking course syllabi and thereby ... -
Tissue-specific extracellular matrix scaffolds for the regeneration of spatially complex musculoskeletal tissues
(2019)Biological scaffolds generated from tissue-derived extracellular matrix (ECM) are commonly used clinically for soft tissue regeneration. Such biomaterials can enhance tissue-specific differentiation of adult stem cells, ... -
The use of small angle light scattering in assessing strain induced collagen degradation in arterial tissue ex vivo
(2018)Collagen is the predominant load bearing component in many soft tissues including arterial tissue and is therefore critical in determining the mechanical integrity of such tissues. Degradation of collagen fibres is ... -
Electrospun Poly-D-L-lactic acid fibrous scaffolds as a delivery vehicle for calcium phosphate salts to promote in situ mineralisation and bone regeneration
(2018)Polymeric scaffolds and calcium phosphate cements have both shown promise in treating bone defects, whereby the former facilitates cell-mediated repair over long periods, while the latter facilitates rapid defect filling ... -
Pressure-induced mesenchymal stem cell osteogenesis is dependent on intermediate filament remodeling.
(2019)Macroscale loading of bone generates a complex local mechanical microenvironment that drives osteogenesis and bone mechanoadaptation. One such mechanical stimulus generated is hydrostatic pressure (HP); however, the effect ... -
The effect of pore size within fibrous scaffolds fabricated using melt electrowriting on human bone marrow stem cell osteogenesis.
(2019)Limitations associated with current bone grafting materials has necessitated the development of synthetic scaffolds that mimic the native tissue for bone repair. Scaffold parameters such as pore size, pore interconnectivity, ... -
The impact of decellularization methods on extracellular matrix derived hydrogels.
(2019)Tissue-derived decellularized biomaterials are ideal for tissue engineering applications as they mimic the biochemical composition of the native tissue. These materials can be used as hydrogels for cell encapsulation and ... -
Potential for combined delivery of riboflavin and all-trans retinoic acid, from silk fibroin for corneal bioengineering.
(2019)Millions of people worldwide suffer from vision impairing conditions resulting from corneal injury or disease. Silk fibroin (SF) is an emerging biopolymer that has been used for several applications including the fabrication ... -
Characterization of extracellular matrix modified poly(¿-caprolactone) electrospun scaffolds with differing fiber orientations for corneal stroma regeneration
(2020)Alternatives to donor cornea transplantation based on tissue engineering are desirable to overcome the current severe donor tissue shortage. Many natural polymers have good biological properties but poor mechanical properties ... -
On-site renewable electricity production and self consumption for manufacturing industry in Ireland: Sensitivity to techno-economic conditions
(2019)The technical and economic feasibility of on-site renewable energy production from solar and wind for a specific manufacturing plant in Ireland is assessed. The energy load of the plant during a typical year is identified ... -
Study of pulsating flow in close-coupled catalyst manifolds using phase-locked hot-wire anemometry
(2004)Phase-locked sampling has been applied to hot-wire anemometry in order to investigate the pulsating flow inside two types of automotive exhaust manifolds fitted with a close-coupled catalyst. An isothermal dynamic flow ... -
Thermal cycling of thermoelectric generators: The effect of heating rate
(2019)Thermoelectric generators, or TEGs, are solid state devices which can convert heat directly into electricity according to the Seebeck effect. When thermoelectric generators are subjected to thermal cycling they can undergo ... -
Facing the Information Leaks in Industrial Water Systems: A Concept for Proxy Measurements to Support Water Metering Audits
(2018)Water optimisation methods and water benchmarking are receiving growing attention in manufacturing surroundings. A basic requirement for any of these approaches is a water metering audit. However, missing ... -
Experimental study of flow dynamics in close-coupled catalyst manifolds
(2007)Time-resolved flow dynamics in an automotive exhaust manifold with close-coupled catalyst are investigated experimentally on a charged motored engine (CME) flow rig. Flow similarity between CME ... -
The theory of critical distances applied to multiscale toughening mechanisms
(2019)The Theory of Critical Distances (TCD) is an approach used for predicting the effect of cracks and notches on fracture and fatigue behaviour. In recent years it has been successfully applied to a wide range of problems ... -
Bio-inspired Aerodynamic Noise Control: A Bibliographic Review
(2019)It is well-known that many species of owl have the unique ability to fly silently, which can be attributed to their distinctive and special feather adaptations. Inspired by the owls, researchers attempted to reduce the ... -
Hybrid additive manufacture of 316L stainless steel with cold spray and selective laser melting: microstructure, mechanical properties and case study
(ASM International, 2019)A novel hybrid additive manufacturing process was proposed and utilized for the production of 316L stainless steel components in this work. It combines selective laser melting (SLM) and cold ... -
The Effect of Calcium and Glucose Concentration on Corneal Epithelial Cell Lines Differentiation, Proliferation, and Focal Adhesion Expression.
(2019)It is known that culture media composition can affect cell behavior, morphology, and gene expression. However,in the case of corneal epithelial cells, the combined role of calcium and glucose concentration in media has not ...
