Mechanical & Manufacturing Eng (Scholarly Publications): Recent submissions
Now showing items 41-60 of 700
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Development and characterization of antacid microcapsules to buffer the acidic intervertebral disc microenvironment
(2024)During intervertebral disc (IVD) degeneration, microenvironmental challenges such as decreasing levels of glucose, oxygen, and pH play crucial roles in cell survival and matrix turnover. Antacids, such as Mg(OH)2 and CaCO3, ... -
Modulation of Inflammation and Regeneration in the Intervertebral Disc Using Enhanced Cell-Penetrating Peptides for MicroRNA Delivery
(2024)Back pain is a global epidemiological and socioeconomic problem affecting up to 80% of people at some stage during their life and is often due to degeneration of the intervertebral disc (IVD). Therapies aimed at restoring ... -
Harmonization and standardization of nucleus pulposus cell extraction and culture methods
(2023)Background In vitro studies using nucleus pulposus (NP) cells are commonly used to investigate disc cell biology and pathogenesis, or to aid in the development of new therapies. However, lab-to-lab variability jeopardizes ... -
Promoting endogenous articular cartilage regeneration using extracellular matrix scaffolds
(2022)Articular cartilage defects fail to heal spontaneously, typically progressing to osteoarthritis. Bone marrow stimulation techniques such as microfracture (MFX) are the current surgical standard of care; however MFX typically ... -
Bilayered extracellular matrix derived scaffolds with anisotropic pore architecture guide tissue organization during osteochondral defect repair
(2022)While some clinical advances in cartilage repair have occurred, osteochondral (OC) defect repair remains a significant challenge, with current scaffold-based approaches failing to recapitulate the complex, hierarchical ... -
Investigation of the surrogate model in an ANN-Meanline Hybrid model for Radial Turbine Performance Prediction
(2024)The ability to efficiently optimise the charging system as part of the complete powertrain for a given duty is attracting significant research interest. A hybrid meanline model integrating Artificial Neural Networks as ... -
LIFE CYCLE ASSESSMENT (LCA) OF A NEWLY DESIGNED METAL ADDITIVE MANUFACTURING PROCESS: MAPS (METAL ADDITIVE MANUFACTURING USING POWDER SHEETS)
(2024)Additive manufacturing (AM), a transformative technology in modern manufacturing, offers design freedom and reduced material waste. However, understanding the environmental impacts of AM processes is imperative for sustainable ... -
Sol–gel‑templated bioactive glass scaffold: a review
(2024)Purpose This review paper explores diverse synthesis strategies within the sol–gel technique for producing silicate bioglass with a focus on tailoring these materials for bone scaffold design. Method A comprehensive ... -
Melt electrowritten scaffold architectures to mimic tissue mechanics and guide neo-tissue orientation
(2024)All human tissues present with unique mechanical properties critical to their function. This is achieved in part through the specific architecture of the extracellular matrix (ECM) fibres within each tissue. An example of ... -
Investigating the Suitability of Multi-Scroll Volutes for Improving Spanwise Incidence of Mixed Flow Turbine Rotors With Varying Blade Cone Angles in Automotive Turbocharging Applications
(2024)Targets to reduce fuel consumption and reduce CO2 emissions have been met using engine downsizing and turbocharging. In automotive applications, it is important that the turbo charger responds well to transient events and ... -
Binder evaporation during powder sheet Additive Manufacturing
(2023)Several Additive Manufacturing methods are well established and found access into regular production in multiple sectors. For processing metals, typically wire or powder is used as feedstock. Wire processing is typically used ... -
Energy Analysis of Fleet Operations using Green Liquid Hydrogen and Synthetic Sustainable Aviation Fuel
(2023)Aircraft designs are changing more rapidly than ever, due to the disruptive technology revolution required to curb harmful emissions, and meet stringent climate targets. As a result, the role of conceptual design tools is ... -
Ultra-broadband sound absorption in a compact multi-chamber micro-perforated panel absorber with varying depths
(2024)This study presents an enhanced multi-chamber micro-perforated panel absorber (MC-MPPA) with varying sub-chamber depths, offering ultra-broadband low-frequency sound absorption. Traditional micro-perforated panel absorbers ... -
Energy Analysis of Fleet Operations Using Green Liquid Hydrogen and Synthetic Kerosene
(2023)This study aims to determine the optimal fuel choice from a well-to-wake energy perspective by means of a comparative energy analysis of real-world fleet operations using green liquid hydrogen and synthetic sustainable ... -
Validation and Calibration of Conceptual Design Tool SUAVE
(2023)The aim of this study is to provide a comprehensive validation of the conceptual design tool SUAVE, with respect to real world flight data from an extensive flight database of 737- 800NG fleet operations. A validation of ... -
Silk fibroin based interpenetrating network hydrogel for corneal stromal regeneration
(2022)There is a need to develop tissue engineering based approaches to address the shortage of donor corneas worldwide for transplantation. To do this a novel approach to fabricate three-dimensional hydrogels using free-radical ... -
Evaluation of bimodal microstructures in selective-laser-melted and heat-treated Ti-6Al-4V
(2023)As-built, SLM-printed Ti-6Al-4V parts suffer from non-equilibrium, brittle microstructures due to the formation of metastable α’-phase martensite as a result of the printing process. Post-processing heat treatments are ... -
Database of 2D materials for specific project purposes
(Trinity College Dublin, 2023) -
Aeroacoustics research in Europe: The CEAS-ASC report on 2022 highlights
(2024)The Council of European Aerospace Societies (CEAS) Aeroacoustics Specialists Committee (ASC) supports and promotes the interests of the scientific and industrial aeroacoustics community on a European scale and European ...
