Mechanical & Manufacturing Eng (Scholarly Publications): Recent submissions
Now showing items 621-640 of 700
-
Low oxygen tension is a more potent promoter of chondrogenic
(2010)During fracture healing and microfracture treatment of cartilage defects mesenchymal stem cells (MSCs) infiltrate the wound site, proliferate extensively and differentiate along a cartilaginous or an osteogenic lineage ... -
The role of mechanical signals in regulating chondrogenesis and osteogenesis of mesenchymal stem cells
(2010)It is becoming increasingly clear that mesenchymal stem cell (MSC) differentiation is regulated by mechanical signals. Mechanical forces generated intrinsically within the cell in response to its extracellular environment, ... -
Implementation of Project Based Learning in a Large Engineering Programme
(2010)The role of the engineer in industry has evolved, with today?s engineering businesses seeking engineers with abilities and attributes in two broad areas - technical understanding and enabling skills. Institutions within ... -
Open Design and the Reprap Project
(2010)This paper details the investigation of an emerging trend within technology development: `open design?. Improvements in communications and computing technology have made collaboration over geographically vast distances ... -
Shear Layer Dynamics of a Cylindrical Cavity for Different Acoustic Resonance Modes
(2010)This paper investigates the interaction between the shear layer over a circular cavity and the flow-excited acoustic response of the volume to shear layer instability modes. Within the fluid-resonant category of cavity ... -
Simulation of angiogenesis and cell differentiation in a CaP scaffold subjected to compressive strains using a lattice modeling approach
(2010)Mechanical stimuli are one of the factors that influence tissue differentiation. In the development of biomaterials for bone tissue engineering, mechanical stimuli and formation of a vascular network that transport oxygen ... -
Technique to Analyze Characteristics of Turbomachinery Broadband Noise Sources (AIAA 2010-3979)
(2010)In this paper an experimental technique for the decomposition of broadband ducted sound fields into their mode constituents is applied to two laboratory scale experimental setups. The broadband mode analysis technique ... -
Shear Layer Driven Acoustic Modes in a Cylindrical Cavity (AIAA 2010-3903)
(2010)Coherence based source analysis techniques can be used to identify the contribution of broadband noise sources in the exhaust of a gas turbine and hence enable the design of noise reduction devices. However, when the ... -
Nonlinear Frequency Scattering of Broadband Noise in Turbomachinery (AIAA 2010-3805)
(2010)Coherence based source analysis techniques can be used to identify the contribution of broadband noise sources in the exhaust of a gas turbine and hence enable the design of noise reduction devices. However, when the ... -
Heat transfer in adjacent interacting impinging synthetic jets
(ASME, 2009)An impinging synthetic jet can attain heat transfer rates comparable to a continuous jet, without net mass input. However it needs a forced cross-flow to supply fresh cooling medium. The vectoring effect of adjacent synthetic ... -
Imaging arterial fibres using diffusion tensor imaging - feasibility study & preliminary results
(2010)MR diffusion tensor imaging (DTI) was used to analyze the fibrous structure of aortic tissue. A fresh porcine aorta was imaged at 7T using a spin echo sequence with the following parameters: matrix 128 ? 128 pixel; slice ... -
The Theory of Critical Distances as an alternative experimental strategy for the determination of KIc and ΔKth
(2010)The present technical note is concerned with the use of the Theory of Critical Distances, applied in the form of the Point Method, to estimate the range of the threshold value of the stress intensity factor, ?Kth, as well ... -
Computational simulation methodologies for mechanobiological modelling: a cell-centred approach to neointima development in stents.
(2010)The design of medical devices could be very much improved if robust tools were available for computational simulation of tissue response to the presence of the implant. Such tools require algorithms to simulate the response ... -
Development of a gait training device for children with cerebral palsy
(2010-04-27)Children with Cerebral Palsy (CP) can generally not walk unaided, but do have some weight bearing ability. Therefore walking aids are often more appropriate than wheelchairs, see figure 1. These devices facilitate mobility ... -
Design Projects in Undergraduate Engineering
(2010)Design has been extensively embedded within the undergraduate Engineering programmes through a restructuring of the curriculum to increase small group, project based learning. Complementing this strategy, a selection of ... -
TEENI-Turboshaft Engine Exhaust Noise Identification
(2010)The TEENI project is an FP7 level 1 (Theme 7 ? Transport) 1st Call EU-funded project. It focuses on Helicopter Engine Exhaust Broadband Noise, and tries to identify the origin of this noise from external measurements only. ... -
The effect of pore size on permeability and cell attachment in collagen scaffolds for tissue engineering.
(IOS Press, 2007)The permeability of scaffolds and other three-dimensional constructs used for tissue engineering applications is important as it controls the diffusion of nutrients in and waste out of the scaffold as well as influencing ... -
Loss of trabeculae by mechano-biological means may explain rapid bone loss in osteoporosis.
(2008)Osteoporosis is characterized by rapid and irreversible loss of trabecular bone tissue leading to increased bone fragility. In this study, we hypothesize two causes for rapid loss of bone trabeculae; firstly, the perforation ... -
A comparison of the osteogenic potential of adult rat mesenchymal stem cells cultured in 2-D and on 3-D collagen glycosaminoglycan scaffolds.
(2007)Adult mesenchymal stem cells (MSCs) have the capability to differentiate along several lineages including those of bone, cartilage, tendon and muscle, thus offering huge potential for the field of tissue engineering. The ... -
Bone tissue material properties are altered during osteoporosis
(Hylonome, 2005)Measurement of the effects of osteoporosis on the mechanical behavior of bone has been performed using whole bone testing, or testing of volumes of ovariectomized cancellous bone1-3 and these studies revealed a decrease ...
