Mechanical & Manufacturing Eng (Scholarly Publications): Recent submissions
Now showing items 661-680 of 700
-
A thermal-hydraulic comparison of liquid microchannel and impinging liquid jet array heat sinks for high power electronics cooling
(IEEE, 2009)In this paper, two single-phase liquid cooling strategies for electronics thermal management are compared and contrasted; impinging jet arrays and laminar flow in microchannels. The comparison is posed for a situation ... -
Rear impact inflicted temporomandibular joint injuries
(Taylor and Francis, 2000)Indirect injuries to the jaw can lead to a range of painful symptoms with serious consequences. These injuries are confirmed by clinical evidence but the injury mechanism is not understood. This work is an investigation ... -
Heat Transfer Enhancement In Ducts Due To Acoustic Excitation
(2009)The thermoacoustic effect that results from the interaction of a sound wave in a compressible fluid in contact with solid boundaries is known to be capable of removing heat from power dissipating systems. In this paper ... -
Prediction of optimal mechanical properties for a scaffold used in osteochondral defect repair
(Mary Ann Liebert, 2006)The optimal mechanical properties of a scaffold to promote cartilage generation in osteochondral defects in vivo are not known. During normal daily activities cartilage is subjected to large cyclic loads that not only ... -
The influence of ventilation tube design on the magnitude of stress imposed at the implant/tympanic membrane interface
(Elsevier, 2008)The design of ventilation tubes or grommets is thought to have a considerable influence on their performance. A computational model (finite element method) was used to investigate the significance of four design parameters ... -
Tissue differentiation and bone regeneration in an osteotomized mandible: a computational analysis of the latency period
(Springer, 2008)Mandibular symphyseal distraction osteogenesis is a common clinical procedure to modify the geometrical shape of the mandible for correcting problems of dental overcrowding and arch shrinkage. In spite of consolidated ... -
Biochemical Markers of the Mechanical Quality of Engineered Hyaline Cartilage
(Springer, 2007)The aim of this study was to determine whether or not biochemical markers can be used as surrogate measures for the mechanical quality of tissue engineered cartilage. The biochemical composition of tissue engineered ... -
A comparative study of shear stresses in collagen-GAG and calcium phosphate scaffolds in bone tissue-engineering bioreactors
(Mary Ann Liebert, 2008)The increasing demand for bone grafts combined with their limited availability and potential risks has led to much new research in bone tissue engineering. Current strategies of bone tissue engineering commonly utilize ... -
Deformation simulation of cells seeded on a collagen-GAG scaffold in a flow perfusion bioreactor using a sequential 3D CFD-elastostatics model.
(2009)Tissue-engineered bone shows promise in meeting the huge demand for bone grafts caused by up to 4 million bone replacement procedures per year, worldwide. State-of-the-art bone tissue engineering strategies use flow perfusion ... -
The effect of prosthesis design on vibration of the reconstructed ossicular chain: a comparative finite element analysis of four prostheses
(Wolters Kluwer, 2003)Hypothesis: We hypothesize that the differences in the bioacoustic performance of ossicular replacement prosthesis designs, and insertion positions, can be quantified using finite element analysis. Background: Many ... -
Biomechanics of ossiculoplasty
(Rila, 2003)Many different designs of prostheses are available for middle ear surgery. Clinical comparisons of such prostheses are often difficult because of the large number of variables involved in the clinical outcome; including ... -
Hydrogen peroxide as a clinical irrigation solution: A comparative study of the effect of hydrogen peroxide versus normal saline on the strength of the bone-cement interface
(IOS Press, 2007)Hydrogen peroxide has been used for decades as an effervescent haemostatic agent in arthroplasty. Recently it has been shown to adversely affect the material properties of PMMA. We aim to assess whether any such deleterious ... -
Effect of a degraded core on the mechanical behaviour of tissue-engineered cartilage constructs: a poro-elastic finite element analysis
(Springer, 2004)The structure and functionality of tissue-engineered cartilage is determined by the tissue culture conditions and mechanical conditioning during growth. The quality of tissue-engineered cartilage can be evaluated using ... -
Mechanobiological models of Skeletal Tissue Differentiation
(Polish Academy of Sciences, 2005)Mechanical forces may act within tissues at the cellular level to regulate biological processes, a field of study that has been termed mechanobiology. The aim of computational mechanobiology is to derive sets of equations ... -
Dynamic compression can inhibit chondrogenesis of mesenchymal stem cells.
(2008)The objective of this study was to investigate the influence of dynamic compressive loading on chondrogenesis of mesenchymal stem cells (MSCs) in the presence of TGF-?3. Isolated porcine MSCs were suspended in 2% agarose ... -
The influence of plaque composition on underlying arterial wall stress during stent expansion: the case for lesion-specific stents
(2009)Intracoronary stent implantation is a mechanical procedure, the success of which depends to a large degree on the mechanical properties of each vessel component involved and the pressure applied to the balloon. Little ... -
Mechano-regulation of stem cell differentiation and tissue regeneration in osteochondral defects
(Elsevier, 2005)Cartilage defects that penetrate the subchondral bone can undergo spontaneous repair through the formation of a fibrous or cartilaginous tissue mediated primarily by mesenchymal stem cells from the bone marrow. This ... -
The influence of expansion rates on mandibular distraction osteogenesis: a computational analysis
(Springer, 2007)Mandibular distraction osteogenesis is a clinical procedure used for modifying the mandibular geometry when problems of dental overcrowding and arch shrinkage occur. The objective of this study is to use a computational ... -
The effect of concentration, cooling rate and cell seeding density on the initial mechanical properties of agarose hydrogels.
(2009)Agarose hydrogels are commonly used for cartilage tissue engineering studies and to provide a three dimensional environment to investigate cellular mechanobiology. Interpreting the results of such studies requires accurate ...
