Browsing Pharmacy and Pharmaceutical Sciences (Theses and Dissertations) by Subject "Active Targeting"
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Design and Synthesis of Potent and Selective Anticancer Compounds Targeting Tubulin Polymerisation and Aminopeptidase N
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2025)This thesis describes the synthesis and evaluation of novel drug conjugates targeting aminopeptidase N (APN) (E.C. 3.4.11.2) and tubulin dynamics. Chapter 1 opens with a thorough review of the existing literature on ...