Browsing Pharmacy and Pharmaceutical Sciences (Theses and Dissertations) by Subject "amorphous"
Now showing items 1-2 of 2
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A Comparison of Spray drying and Liquid Antisolvent Co-precipitation for the Generation of Two- and Three- component Amorphous Solid Dispersions
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2024)The thesis focuses on the use of different manufacturing techniques for the generation of amorphous solid dispersions (ASDs) for the enhancement of the solubility of model compounds. ASDs with hydrochlorothiazide (HCTZ) ... -
The production and characterisation of itraconazole multicomponent systems
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2019)This thesis focuses on the poorly soluble triazole antifungal agent, itraconazole (ITZ). This compound was reported to form hydrochloride salts and cocrystals with a wide range of aliphatic dicarboxylic acids, which have ...
