Pharmacy and Pharmaceutical Sciences (Scholarly Publications): Recent submissions
Now showing items 41-60 of 452
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High-Pressure Dielectric Studies-a Way to Experimentally Determine the Solubility of a Drug in the Polymer Matrix at Low Temperatures
(2021)In this work, we employed broad-band dielectric spectroscopy to determine the solubility limits of nimesulide in the Kollidon VA64 matrix at ambient and elevated pressure conditions. Our studies confirmed that the solubility ... -
Formation of low melting point binary systems comprising ketoprofen and an amide local anaesthetic
(2021)Liquid forms of active pharmaceutical ingredients, ionic liquids (ILs) and deep eutectic mixtures (DEMs), offer several potential benefits in respect to advancing pharmaceutical formulations. The aim of this study was to ... -
Formation of stoichiometric and non-stoichiometric ionic liquid and cocrystal multicomponent phases of lidocaine with azelaic acid by changing counterion ratios
(2021)Tuning of physicochemical properties of ionic liquids and crystalline materials is a challenge that opens up unlimited possibilities for expanding applications and controlling biological activity of pharmaceutical ... -
Personal Electronic Records of Medications (PERMs) for medication reconciliation at care transitions: a rapid realist review.
(2021)Background Medication reconciliation (MedRec), a process to reduce medication error at care transitions, is labour- and resource-intensive and time-consuming. Use of Personal Electronic Records of Medications (PERMs) ... -
Extracellular vesicle separation from milk and infant milk formula using acid precipitation and ultracentrifugation
(2021)Separation of highly enriched extracellular vesicles (EVs) fractions from milk is desirable for quantification, cargo analysis, functional characterization, and investigation as delivery vehicles for nutrients and/or ... -
Evidence for the Need to Evaluate More Than One Source of Extracellular Vesicles, Rather Than Single or Pooled Samples Only, When Comparing Extracellular Vesicles Separation Methods
(2021)To study and exploit extracellular vesicles (EVs) for clinical benefit as biomarkers, therapeutics, or drug delivery vehicles in diseases such as cancer, typically we need to separate them from the biofluid into which they ... -
The relationship between antiepileptic drug load and challenging behaviors in older adults with intellectual disability and epilepsy
(2021)Antiepileptic drugs (AEDs) may affect mood and behavior in people with epilepsy and intellectual disability. A high AED load, derived from AED polytherapy and/or high doses of AEDs, has been suggested to be a risk factor ... -
Pharmacists involvement in COVID-19 vaccination across Europe: A situational analysis of current practice and policy
(2021)One year since the emergence of the COVID-19 pandemic, rapid response measures have been implemented internationally to mitigate the spread of the virus. Following rapid and successful pre-clinical and human trials, several ... -
Do assorted approaches aid in estimation of uronic acids? Case studies on Tinospora sinensis polysaccharides
(2014)Polysaccharides containing uronic acids are of immense biological significance. Colorimetric methods using different chromogens have been explored for uronic acid estimation in polysaccharides but these methods counter ... -
The antiviral potential of algal-derived macromolecules
(2021)A diverse range of molecules with anticancer, antiviral, and antibiotic activities has been identified and isolated from algal species. Such metabolites could address unmet clinical needs and be used to fight human diseases. ... -
Upgrading Methylation Method for Structural Studies of Polysaccharides: Case Analysis of a Bioactive Polysaccharide from Acacia tortilis.
(2020)Methylation has been the most widely used conventional tool in the structural characterization of polysaccharides. In the series of developments in methylation methods employing a diverse range of solvents and methylating ... -
Studies on Tinospora cordifolia monosugars and correlation analysis of uronic acids by spectrophotometry and GLC
(2014)Cold water-soluble (CWSP) and hot water soluble polysaccharides (HWSP) from Tinospora cordifolia stems were isolated and purified in 2.99% and 1.99% yield respectively. Complete hydrolysis followed by paper chromatography ... -
Extracellular polymeric substances in antarctic environments: A review of their ecological roles and impact on glacier biogeochemical cycles.
(2021)Antarctic continent comprises diverse ecosystems like snow, glacier ice, sea ice, melt pools, glacial soils, supraglacial and subglacial lakes that accommodate numerous microbial and algal communities. These biotic groups ... -
A Unique Polysaccharide containing 3-O-Methylarabinose and 3-O-Methylgalactose from Tinospora sinensis
(2018)Tinospora sinensis (Lour.) Merrill is of great therapeutic significance in Indian traditional medicine. Crude polysaccharides were isolated from methanol pre-extracted stems of dried material by successive extractions with ... -
Phytochemicals from food plant residues an approach to environmental clean-up.
(2011)Increased consumption of ‘ready to eat’ foods in modern lifestyle has resulted in several health problems. Natural health-protective and disease-preventive products are in great demand nowadays due to both consumers’ ... -
Experiences of the Medication Use Process by People with Intellectual Disabilities. What a Pharmacist Should Know!
(2021)There is a scarcity of information about the experience of people with intellectual disabilities in the medication use process. Six people with intellectual disabilities consented to be interviewed by a pharmacist to ... -
Defensive Pharmacy Practice: A Gap in our Understanding
(2021)Defensive practice is prevalent across healthcare disciplines and much study has been performed on this behaviour in medicine and nursing. However, little research has been carried out on defensive practice in pharmacy, ... -
A call for the standardised reporting of factors affecting the exogenous loading of extracellular vesicles with therapeutic cargos
(2021)Extracellular vesicles (EVs) are complex nanoparticles required for the intercellular transfer of diverse biological cargoes. Unlike synthetic nanoparticles, EVs may provide a natural platform for the enhanced targeting ... -
Biocompatible copolymer formulations to treat glioblastoma multiforme.
(2021)The treatment for glioblastoma multiforme (GBM) has not changed for more than 20 years while the prognosis for the patients is still poor and most of them survive less than 1 year after diagnosis. The standard of care for ...
