Browsing Pharmacognosy (Theses and Dissertations) by Title
Now showing items 6-7 of 7
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Synthesis and pharmacological studies on a novel series of mast cell-stabilising tetrahydronaphthalenes and related compounds
(Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2003)The purpose of this thesis was the design, synthesis and pharmacological screening of a novel series of tetrahydronapthalene molecules for mast cell-stabilising activity. The introductory Chapter commences with a discussion ... -
The design and synthesis of novel inhibitors of tubulin polymerisation
(Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2003)This thesis is introduced with a review on the principles of tubulin polymerisation and how this process is necessary for cellular replication. This leads on to discussion of the structure-activity relationships of known ...