Administrative Staff Authors : Recent submissions
Now showing items 301-320 of 840
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Mouse and human genetic analyses associate kalirin with ventral striatal activation during impulsivity and with alcohol misuse
(2016)Impulsivity is associated with a spectrum of psychiatric disorders including drug addiction. To investigate genetic associations with impulsivity and initiation of drug taking, we took a two-step approach. First, we ... -
A translational systems biology approach in both animals and humans identifies a functionally related module of accumbal genes involved in the regulation of reward processing and binge drinking in males.
(2015)Background: The mesolimbic dopamine system, composed primarily of dopaminergic neurons in the ventral tegmental area that project to striatal structures, is considered to be the key mediator of reinforcement-related ... -
Early hippocampal volume loss as a marker of eventual memory deficits caused by repeated stress
(2016)Exposure to severe and prolonged stress has detrimental effects on the hippocampus. However, relatively little is known about the gradual changes in hippocampal structure, and its behavioral consequences, over the course ... -
Cannabis use in early adolescence: Evidence of amygdala hypersensitivity to signals of threat
(2015)Cannabis use in adolescence may be characterized by differences in the neural basis of affective processing. In this study, we used an fMRI affective face processing task to compare a large group (n = 70) of 14-year olds ... -
Brain Regions Related to Impulsivity Mediate the Effects of Early Adversity on Antisocial Behavior
(2017)Background Individual differences in impulsivity and early adversity are known to be strong predictors of adolescent antisocial behavior. However, the neurobiological bases of impulsivity and their relation to antisocial ... -
Exploring the challenges experienced by people with muscular dystrophy living independently (MD INDOLIVING)
(University of Dublin Trinity College, 2016)This study follows up on the national survey undertaken in 2014 by Muscular Dystrophy Ireland (MDI) in which a questionnaire was distributed to all MDI members (n=697). Significantly, 69% of respondents reported that ... -
Age-Related Sexual Dimorphism in Temporal Discrimination and in Adult-Onset Dystonia Suggests GABAergic Mechanisms.
(2015)BACKGROUND: Adult-onset isolated focal dystonia (AOIFD) presenting in early adult life is more frequent in men, whereas in middle age it is female predominant. Temporal discrimination, an endophenotype of adult-onset ... -
Liquid exfoliation of solvent-stabilized few-layer black phosphorus for applications beyond electronics.
(2015)Few-layer black phosphorus (BP) is a new two-dimensional material which is of great interest for applications, mainly in electronics. However, its lack of environmental stability severely limits its synthesis and processing. ... -
Dementia in older people admitted to hospital: a regional multi-hospital observational study of prevalence, associations and case recognition.
(2015)Previous studies have indicated a prevalence of dementia in older admissions of ∼42% in a single London teaching hospital, and 21% in four Queensland hospitals. However, there is a lack of published data from any European ... -
Neural correlates of abnormal sensory discrimination in laryngeal dystonia.
(2016)Aberrant sensory processing plays a fundamental role in the pathophysiology of dystonia; however, its underpinning neural mechanisms in relation to dystonia phenotype and genotype remain unclear. We examined temporal and ... -
A Deep Look Into Erionite Fibres: an Electron Microscopy Investigation of their Self-Assembly.
(2015)The exposure of humans to erionite fibres of appropriate morphology and dimension has been unambiguously linked to the occurrence of Malignant Mesothelioma. For this reason, a detailed morpho-structural investigation through ... -
Temporal Cortex Morphology in Mesial Temporal Lobe Epilepsy Patients and Their Asymptomatic Siblings
(2016)Temporal cortex abnormalities are common in patients with mesial temporal lobe epilepsy due to hippocampal sclerosis (MTLE+HS) and believed to be relevant to the underlying mechanisms. In the present study, we set out to ...
