Chemistry: Recent submissions
Now showing items 41-60 of 1366
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Porphyrin Atropisomerism as a Molecular Engineering Tool in Medicinal Chemistry, Molecular Recognition, Supramolecular Assembly, and Catalysis
(2024)Porphyrin atropisomerism, which arises from restricted σ-bond rotation between the macrocycle and a sufficiently bulky substituent, was identified in 1969 by Gottwald and Ullman in 5,10,15,20-tetrakis(o-hydroxyphenyl)porphyrins. ... -
The Covalent Capture of [2]Catenanes Using Self-Templating Allyl Amide-Appended 2,6-bis(triazol-4-yl)pyridines
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2025)This thesis, entitled "The Covalent Capture of [2]Catenanes Using Self-Templating Allyl Amide-Appended 2,6-bis(triazol-4-yl)pyridines" describes the synthesis of self-templating [2]catenanes using the N-allyl-4-methylene ... -
Synthesis, biological evaluation, and docking studies of pyrazole-linked benzothiazole hybrids as promising anti-TB agents
(2024)Tuberculosis (TB) is a global pandemic killing millions of people every year. Yet, resistant strains make curing TB quite challenging. Herein, a series of new pyrazole-linked benzothiazole hybrids was synthesized and ... -
Synthesis and Testing of Lipopeptide and Peptide Probes for Bacterial Lipoprotein Processing Enzymes
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2025)Bacterial lipoproteins perform essential functions in bacteria and are often crucial for survival, growth and virulence. Bacterial lipoproteins feature a fully conserved N-terminal cysteine bearing a 1,2-diacylglyceryl ... -
C–C Coupling in sterically demanding porphyrin environments
(2024)Unlike their planar counterparts, classic synthetic protocols for C–C bond forming reactions on nonplanar porphyrins are underdeveloped. The development of C–C bond forming reactions on nonplanar porphyrins is critical in ... -
Fine-tuning of radiative properties by “mild” substituents: searching for a perfectly soft chromophore
(2024)Controlling spectral properties to achieve desired characteristics is an attractive goal in application- oriented research, e.g., in the design of fluorescence sensors. ‘‘Soft’’ chromophores, molecules with strong spectral ... -
Understanding and Controlling Molecular Compositions and Properties in Mixed-Linker Porphyrin Metal-Organic Frameworks
(2024)Porphyrin-based metal-organic frameworks (MOFs) are attractive materials for photo- and thermally activated catalysis due to their unique structural features related to the porphyrin moiety, guest accessible porosity and ... -
Antitumor Immunity Mediated by Photodynamic Therapy Using Injectable Chitosan Hydrogels for Intratumoral and Sustained Drug Delivery
(2024)Photodynamic therapy (PDT) is an anticancer therapy with proven efficacy; however, its application is often limited by prolonged skin photosensitivity and solubility issues associated with the phototherapeutic agents. ... -
Rational catalyst design for photo- and electrochemical hydrogenation reactions
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2025)Environmental pollution is an urgent threat to human health and the survival of life forms on land and in water. This crisis is fuelled by industrial, agricultural, and biomedical chemical waste, alongside the use of ... -
The Fabrication of Highly Conducting and Thermo-mechanically Robust Metal Thin Film
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2025)Recent research from high-resolution surface probe microscopy and atomic simulation have identified that grain boundaries in [111] F.C.C. thin copper films can restructure in a region immediately below the surface. DFT ... -
Thioacid Mediated Methods for Peptide Ligation and Cyclisation
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2025)In recent years, peptide-based therapeutics have become the focus of intensive research due to their favourable chemical properties. Consequently, the ability to efficiently synthesise a wide range of structurally diverse ... -
Electrical and structural characterisation of Transition Metal Dichalcogenides
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2025)This thesis explores modification of transition metal dichalcogenides (TMDs) through doping and synthesis techniques to tailor their electronic properties, including sensor technology. The work is divided into three main ... -
Investigation of Copper/Graphene Composite Materials for Enhanced Electrical Conductivity Applications
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2025)Copper plays a vital and ever-growing role in electrical power and signal transmission in the world today. This is due to its remarkable electrical properties, coupled with its low cost and abundance. In order to satisfy ... -
Dataset of the manuscript Electrocatalytic hydrogenation of unsaturated organics using Mo and W porous carbon-encapsulated nanostructures: impact of metal type on properties and performances
(Trinity College Dublin, 2024)The present dataset is composed of 6 different methods used for the measurements, characterizations, and analysis: 1) X-ray diffraction (XRD): This dataset includes raw measurements for RPM/BP, W@C:N, and Mo@C:N. Each ... -
Porous N-Doped Carbon-encapsulated Iron as Novel Catalyst Architecture for the Electrocatalytic Hydrogenation of Benzaldehyde
(2024)Carbon porous materials containing nitrogen functionalities and encapsulated iron-based active sites have been suggested as electrocatalysts for energy conversion, however their applications to the hydrogenation of ... -
Dataset for Single-Entity Electrochemistry of N-Doped Graphene Oxide Nanostructures for Improved Kinetics of Vanadyl Oxidation
(Trinity College Dublin, 2024)The present dataset is composed of 7 different methods used for the measurements, characterizations, and analysis of our article: 1) Literature review: This dataset describes the literature review of vanadyl oxidation on ... -
Single-Entity Electrochemistry of N-Doped Graphene Oxide Nanostructures for Improved Kinetics of Vanadyl Oxidation
(2024)N-doped graphene oxides (GO) are nanomaterials of interest as building blocks for 3D electrode architectures for vanadium redox flow battery applications. N- and O-functionalities have been reported to increase charge ... -
Dataset associated to Effects of N-functional groups on the electron transfer kinetics of VO2+/VO2+ at carbon: Decoupling morphology from chemical effects using model systems
(Colavita Laboratory, Trinity College Dublin, 2023)The present dataset is composed of 5 different methods used for the measurements, characterizations, and analysis of our article: 1) X-ray photoelectron spectroscopy (XPS): This dataset describes the elemental composition ...
