Chemistry: Recent submissions
Now showing items 81-100 of 1366
-
Engineered Self-Assemblies from Synthetic Tripodal Ligands for the Formation Soft Materials with Desirable Properties
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, Trinity College Dublin, School of Chemistry, 2024)This thesis, entitled “Engineered Self-Assemblies from Synthetic Tripodal Ligands for the Formation of Soft Materials with Desirable Properties” describes the synthesis and characterisation of various novel benzene-1,3 ... -
Furazano[3,4-d]pyrimidines and phosphazene pteridines as new tools in organic chemistry
(Trinity College (Dublin, Ireland). School of Chemistry, 1998)This thesis explores the use of 5,7-diaminofurazano[3,4-d]pyrimidine (64) (R = NH2) for the design of a pro-drug system which is stable in media of pH less than 5 but releases the active drug at pH values greater than 5. ... -
An Investigation of the Self-Assembly of Luminescent Lanthanide Architectures Using Novel Triazole-Pyridine Derivatives
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2024)Supramolecular assemblies based on some lanthanide ions (Ln = Nd(III), Sm(III), Eu(III), Tb(III), Dy(III), Er(III), Tm(III), Yb(III)) may have luminescent properties and have shown promise in applications such as sensing, ... -
Strategies to Stabilise Peptide Secondary Structure Using Unnatural Amino Acid Crosslinking
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2024)The communication between proteins plays a pivotal role in both biological and pathological processes. Protein-protein interactions (PPIs) play crucial roles in transcription, signal transduction and apoptosis; as such, ... -
Synthetic Routes to Greener Pastures: A Sustainable View Towards Biomedically Relevant Magnetic Nanomaterials
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2024)Magnetic nanomaterials such as the spinel-type oxides, MFe2O4 (M = Fe2+, Co2+, Ni2+, Zn2+) have emerged as key materials in nanomedicine, with highly tuneable properties, accessed by varying composition or surface modification ... -
Searching for “Greener” Bioequivalents of CF3 to Lower its Environmental Impact
(2024)Considering the broad use of the trifluoromethyl functional group (−CF3) in medicinal chemistry and taking into account the recent concerns on the negative environmental effects of CF3 containing compounds, we are searching ... -
Balancing Innovation with Environmental Sustainability: Vapour Phase Patterning System for Controlling Block Co-Polymer and Polymer Brush Morphology
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2024)The growth of the semiconductor industry and device miniaturisation has highlighted a need for novel and sustainable approaches to nanofabrication. Resource scarcity, increasing energy costs and environmental instability ... -
High Resolution Lithography Techniques for Applications in Plasmonic Nanomaterials
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2024)Metallic nanoparticles are of great scientific interest owing to their ability to support collective oscillations of electrons across their surface, known as localised surface plasmon resonances (LSPRs), when illuminated ... -
Novel Ionic Organocatalysts for Asymmetric Peptide Synthesis and Plastic Recycling
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2024)In the past century, peptide therapeutics have been introduced as a powerful alternative to small molecule drugs; their ability to form strong interactions with proteins has led to their use in the treatment of many ... -
Theoretical Insights into Ammonia Production and Conversion via Heterogeneous Catalysis
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2024)The global population is heavily dependent upon the production of ammonia via the Haber-Bosch process. This is an environmentally unfriendly process that demands pure hydrogen, obtained from the steam reforming of methane. ... -
Wedge disclination description of emergent core-shifted grain boundaries at free surfaces
(2023)Emergent grain boundaries at free surface control material properties such as nanomaterial strength, catalysis, and corrosion. Recently the restructuring of emergent boundaries on copper (111) surfaces was discovered ... -
Micro and nano plastics release from a single absorbable suture into simulated body fluid
(2024)Synthetic polymers are widely used in medical devices and implants where biocompatibility and mechanical strength are key enablers of emerging technologies. One concern that has not been widely studied is the potential of ... -
Liquid Phase Exfoliation, characterization, and printing of SnSe and PtSe2 devices
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2024)The demand for optical-to-electrical and/or electrical-to-optical transducers is growing exponentially as optics are increasingly adopted for energy-efficient data transmission. Displays and light sensors are increasingly ... -
Core shift controls grain boundary energy scaling in Cu and Al
(2024)Grain boundary energies in different elements are correlated. The proportional scaling constants relating the energies of crystallography-equivalent boundaries in any two f.c.c. elements are nearly constant, with the ... -
Characterisation of Structure-Property Relationships in Novel Chalcogenides Systems
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2024)As devices become smaller and head towards the atomic limits, minute changes in their structure, in the form of defects, can have an oversized effect on the device properties. This is especially true for novel classes of ... -
High levels of microparticles release from biodegradable polylactic acid paper cups compared with polyethylene-lined cups
(2023)Polylactic acid (PLA) is a popular replacement for conventional fossil-fuel based plastics products such as polyethylene (PE) due to its high biodegradability and recyclability. Previous studies confirmed that PLA microplastics ... -
Exploring the Diverse Landscape of Layered Double Hydroxide-Based Nanomaterials
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, Trinity College Dublin, School of Chemistry, 2024)This thesis details the synthesis, characterisation, and an exploration of the diverse application landscape of layered double hydroxide (LDH)-based nanomaterials. The aim is to showcase the potential of LDHs in chirality ... -
Nucleoside and Oligonucleotide Modification for Targeting the DNA Damage Repair Enzyme SNM1A
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2024)The exonuclease SNM1A is a key enzyme involved in the repair of interstrand crosslinks, a highly cytotoxic form of DNA damage. As cells depleted in this enzyme display increased sensitivity to chemotherapeutic agents such ... -
Exploring new techniques for the surface modification of high-performance polymer materials
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2024)The surface modification of high-performance polymers is a critical area of research, as these materials possess excellent mechanical, chemical, and thermal properties but often lack the surface functionality required for ... -
Novel Chemical Modalities and Methods for Protein Profiling
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2024)The activity of proteins is pivotal to the chemistry of cells. In order to deconvolute the complexity of living systems, chemical tools can be used to study active proteins under different cellular states. Amongst these ...
