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dc.contributor.authorO'Morain, Colmen
dc.contributor.authorKennedy, Nicholasen
dc.contributor.authorKelleher, Dermoten
dc.contributor.authorMc Manus, Rossen
dc.date.accessioned2009-10-05T18:09:48Z
dc.date.available2009-10-05T18:09:48Z
dc.date.issued2008en
dc.date.submitted2008en
dc.identifier.citationHunt KA, Zhernakova A, Turner G, Heap GA, Franke L, Bruinenberg M, Romanos J, Dinesen LC, Ryan AW, Panesar D, Gwilliam R,Takeuchi F, McLaren WM, Holmes GK, Howdle PD, Walters JR, Sanders DS, Playford RJ, Trynka G, Mulder CJ, Mearin ML,Verbeek WH, Trimble V, Stevens FM, O'Morain C, Kennedy NP, Kelleher D, Pennington DJ, Strachan DP, McArdle WL, Mein CA,Wapenaar MC, Deloukas P, McGinnis R, McManus R*, Wijmenga C*, van Heel DA*., Newly identified genetic risk variants for celiac disease related to the immune response., Nature Genetics, 40, 2008, 395-402en
dc.identifier.otherYen
dc.descriptionPUBLISHEDen
dc.description* Joint Senior Authorsen
dc.description.sponsorshipWe acknowledge funding from Coeliac UK (to DAvH); the Coeliac Disease Consortium (an innovative cluster approved by the Netherlands Genomics Initiative and partly funded by the Dutch Government, grant BSIK03009 to CW); the European Union (STREP 036383); the Netherlands Organization for Scientific Research (VICI grant 918.66.620 to CW); the Science Foundation Ireland; the Irish Health Research Board; Hitachi Europe Ltd.; and the Wellcome Trust (GR068094MA Clinician Scientist Fellowship to DAvH; New Blood Fellowship to RMcM; support for the work of RMcG and PD). We thank the Barts and The London Genome Centre for genotyping support; J Swift, P. Kumar, D.P. Jewell, S.P.L. Travis, K. Moriarty for collection of UKGWAS and additional samples. We acknowledge use of DNA from the British 1958 Birth Cohort collection, funded by the UK Medical Research Council grant G0000934 and the Wellcome Trust grant 068545/Z/02.. We thank A. Monsuur for patient recruitment, G. Meijer and J. Meijer for histology review, K. Duran for DNA extraction, H. van Someren and F. Mulder for clinical database management, M. Plateel and the Genotyping facilities at UMCG and UMC Utrecht for technical assistance (the Netherlands). We thank M. Abuzakouk, R. McLoughlin, K. Brophy, C. Feighery, J. McPartlin for sample collection. Irish Control DNA was supplied by Irish Blood Transfusion Service/Trinity College Dublin Biobank. We thank the Wellcome Trust Centre for Human Genetics, University of Oxford for provision of computing facilities and G. McVean for recombination rate data. We thank all celiac and control individuals for participating in this study.en
dc.format.extent395-402en
dc.format.mimetypeapplication/pdf
dc.language.isoenen
dc.relation.ispartofseriesNature Geneticsen
dc.relation.ispartofseries40en
dc.rightsYen
dc.subjectGenetics
dc.titleNewly identified genetic risk variants for celiac disease related to the immune response.en
dc.typeJournal Articleen
dc.type.supercollectionscholarly_publicationsen
dc.type.supercollectionrefereed_publicationsen
dc.identifier.peoplefinderurlhttp://people.tcd.ie/kellehdpen
dc.identifier.peoplefinderurlhttp://people.tcd.ie/omoraincen
dc.identifier.peoplefinderurlhttp://people.tcd.ie/rmcmanusen
dc.identifier.peoplefinderurlhttp://people.tcd.ie/nkennedyen
dc.identifier.rssinternalid61793en
dc.identifier.doihttp://dx.doi.org/10.1038/ng.102en
dc.subject.TCDThemeGenes & Societyen
dc.subject.TCDThemeImmunology, Inflammation & Infectionen
dc.subject.TCDThemeInternational Developmenten
dc.identifier.rssurihttp://dx.doi.org/10.1038/ng.102
dc.identifier.urihttp://hdl.handle.net/2262/33793


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