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dc.contributor.authorFAGAN, ANDREW JOHNen
dc.date.accessioned2011-06-14T13:46:12Z
dc.date.available2011-06-14T13:46:12Z
dc.date.issued2011en
dc.date.submitted2011en
dc.identifier.citationD.M. King, C.M. Moran, J. McNamara, A.J. Fagan and J.E. Browne, Development of a vessel-mimicking material for use in anatomically realistic Doppler flow phantoms, Ultrasound in Medicine and Biology, 37, 5, 2011, 813 - 826en
dc.identifier.otherYen
dc.descriptionPUBLISHEDen
dc.description.abstractPolyvinyl alcohol cryogel, (PVA-C) is presented as a vessel mimicking material for use in anatomically realistic Doppler flow phantoms. Three different batches of 10 % wt PVA-C containing (i) PVA-C alone, (ii) PVA C with anti-bacterial agent and (iii) PVA-C with silicon carbide particles were produced, each with 1 to 6 freeze-thaw cycles. The resulting PVA-C samples were characterized acoustically (over a range 2.65 ? 10.5 MHz) and mechanically in order to determine the optimum mixture and preparation for mimicking the properties of healthy and diseased arteries found in vivo. This optimum mix was reached with the PVA-C with anti-bacterial agent sample, prepared after 2 freeze/thaw cycles, which achieved a speed of sound of 1538 ? 5 m s 1 and a Young?s elastic modulus of 79 ? 11kPa. This material was used to make a range of anatomically-realistic flow phantoms with varying degrees of stenoses, and subsequent flow experiments revealed that higher degrees of stenoses and higher velocities could be achieved without phantom rupturing compared to a phantom containing conventional wall-less vessels.en
dc.description.sponsorshipThis work was supported by the Technological Sector Research Strand 1 Scheme, HEA and the TERs 2005 and CABS 2007 Schemes, Research Support Unit, Dublin Institute of Technology. CMM would like to acknowledge funding from the British Heart Foundation (PG/07/107) and the advice and use of physical test facilities provided by Dr Thomas Alshuth and Peter Erren of the Deutsches Institut fur Kautschuktechnologie e.V. (Hannover).en
dc.format.extent813en
dc.format.extent826en
dc.language.isoenen
dc.relation.ispartofseriesUltrasound in Medicine and Biologyen
dc.relation.ispartofseries37en
dc.relation.ispartofseries5en
dc.rightsYen
dc.subjectPolyvinyl alcohol cryogelen
dc.subjectanatomically realistic flow phantomen
dc.subjectvessel mimicen
dc.subjectacoustic and mechanical characterisationen
dc.titleDevelopment of a vessel-mimicking material for use in anatomically realistic Doppler flow phantomsen
dc.typeJournal Articleen
dc.type.supercollectionscholarly_publicationsen
dc.type.supercollectionrefereed_publicationsen
dc.identifier.peoplefinderurlhttp://people.tcd.ie/fagananen
dc.identifier.rssinternalid72594en
dc.identifier.rssurihttp://dx.doi.org/10.1016/j.ultrasmedbio.2011.02.012en
dc.contributor.sponsorHigher Education Authorityen
dc.contributor.sponsorGrantNumberPG/07/107/23895en
dc.contributor.sponsorBritish Heart Foundation (BHF)en
dc.identifier.urihttp://hdl.handle.net/2262/56863


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