Browsing School of Engineering by Author "O'BRIEN, FERGAL"
Now showing items 1-11 of 11
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Biomaterial based modulation of macrophage polarization: A review and suggested design principles
KELLY, DANIEL; O'BRIEN, FERGAL (2015)Macrophages have long been known for their phagocytic capabilities and immune defence; however, their role in healing is being increasingly recognized in recent years due to their ability to polarize into pro-inflammatory ... -
The effect of bisphosphonate treatment on the biochemical and cellular events during bone remodelling in response to microinjury stimulation
TAYLOR, DAVID; O'BRIEN, FERGAL (2015)Osteoporosis is one of the most prevalent bone diseases worldwide and is characterised by high levels of bone turnover, a marked loss in bone mass and accumulation of microdamage, which leads ... -
The effect of pore size on permeability and cell attachment in collagen scaffolds for tissue engineering.
Prendergast, Patrick John; O'BRIEN, FERGAL (IOS Press, 2007)The permeability of scaffolds and other three-dimensional constructs used for tissue engineering applications is important as it controls the diffusion of nutrients in and waste out of the scaffold as well as influencing ... -
Fibrin hydrogels functionalized with cartilage extracellular matrix and incorporating freshly isolated stromal cells as an injectable for cartilage regeneration
KELLY, DANIEL; BUCKLEY, CONOR; O'BRIEN, FERGAL; CUNNIFFE, GRÁINNE (2016) -
Gene Delivery of TGF-?3 and BMP2 in an MSC-Laden Alginate Hydrogel for Articular Cartilage and Endochondral Bone Tissue Engineering
KELLY, DANIEL; O'BRIEN, FERGAL; CUNNIFFE, GR?INNE (2016) -
Infrapatellar Fat Pad Stem Cells: From Developmental Biology to Cell Therapy
KELLY, DANIEL; O'BRIEN, FERGAL (2017) -
Mesenchymal stem cell fate following non-viral gene transfection strongly depends on the choice of delivery vector
KELLY, DANIEL; NICOLOSI, VALERIA; CUNNIFFE, GR?INNE; O'BRIEN, FERGAL (2017) -
Part 1: scaffolds and surfaces.
O'BRIEN, FERGAL (Elsevier, 2008)Every day thousands of clinical procedures are performed to replace or repair tissues in the human body that have been damaged through disease or trauma. Current therapies are focused on the replacement of the damaged ... -
Porous decellularized tissue engineered hypertrophic cartilage as a scaffold for large bone defect healing
KELLY, DANIEL; VINARDELL, TATIANA; CUNNIFFE, GR?INNE; O'BRIEN, FERGAL (2015)Clinical translation of tissue engineered therapeutics is hampered by the significant logistical and regulatory challenges associated with such products, prompting increased interest in the use of decellularized extracellular ... -
Porous Scaffolds Derived from Devitalized Tissue Engineered Cartilaginous Matrix Support Chondrogenesis of Adult Stem Cells
KELLY, DANIEL; O'BRIEN, FERGAL (2017) -
Stem cells display a donor dependent response to escalating levels of growth factor release from extracellular matrix-derived scaffolds
KELLY, DANIEL; O'BRIEN, FERGAL (2016)