Photophysical and biological investigation of novel luminescent Ru(II)-polypyridyl-1,8-naphthalimide Troger's bases as cellular imaging agents

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Journal Article
Date:
2012
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Elmes, RBP, Erby, M, Bright, SA, Williams, DC, Gunnlaugsson, T, Photophysical and biological investigation of novel luminescent Ru(II)-polypyridyl-1,8-naphthalimide Troger's bases as cellular imaging agents, CHEMICAL COMMUNICATIONS, 48, 20, 2012, 2588-2590
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Abstract:
The synthesis and photophysical properties of 1 and 2, two Ru(ii)-polypyridyl based-1,8-naphthalimide Troger's bases, are described; these were found to stabilize double stranded DNA, undergo rapid cellular uptake, displaying good luminescence without affecting cell viability even after 24 hours of incubation.
URI:
http://hdl.handle.net/2262/67315
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Grant Number
Science Foundation Ireland (SFI)
SFI RFP 2009
Science Foundation Ireland (SFI)
SFI 2010 PI
Author's Homepage:
http://people.tcd.ie/gunnlaut
Description:
PUBLISHED
Author: GUNNLAUGSSON, THORFINNUR
Sponsor:
Science Foundation Ireland (SFI)
Science Foundation Ireland (SFI)
Type of material:
Journal Article
URI:
http://hdl.handle.net/2262/67315
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Series/Report no:
CHEMICAL COMMUNICATIONS
48
20
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Subject:
double stranded DNA; luminescent agent; naphthalimide derivative; ruthenium complex; Troger base; unclassified drug
DOI:
http://dx.doi.org/10.1039/c2cc17274g
ISSN:
1359-7345
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