Browsing RSS Feeds by Author "PALSSON MCDERMOTT, EVA"
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Glucocorticoids inhibit IRF3 phosphorylation in response to Toll-like
O'NEILL, LUKE ANTHONY JOHN; CARPENTER, SUSAN; PALSSON MCDERMOTT, EVA (2008)Phosphorylation of the transcription factor interferon regulatory factor 3 (IRF3) is essential for the induction of promoters which contain the interferon-stimulated response element (ISRE). IRF3 can be activated by Toll-like ... -
NF-kappaB activation by the Toll-IL-1 receptor domain-containing protein Mal is regulated by caspase-1
O'NEILL, LUKE ANTHONY JOHN; PALSSON MCDERMOTT, EVA; BANAHAN, KATHY; DUNNE, AISLING (2007)Toll-like receptors (TLRs)-2 and -4 are important proteins in innate immunity, recognizing microbial products and eliciting host defense responses. Both use the adapter proteins MyD88 and MyD88 adapter-like (Mal) to activate ...