RSS Feeds: Recent submissions
Now showing items 21-40 of 13950
-
Truncated Turbo Equalizer with SIC for OTFS
(2023)Orthogonal time frequency space (OTFS) is a promising candidate waveform for the next generation wireless communication systems. OTFS places data in the delay-Doppler (DD) domain, which simplifies channel estimation in ... -
RIS Meets Aerodynamic HAPS: A Multi-Objective Optimization Approach
(2023)In this letter, we propose a novel network architecture for integrating terrestrial and non-terrestrial networks (NTNs) to establish connection between terrestrial ground stations which are unconnected due to blockage. ... -
The New Anticipatory Governance Culture for Innovation: Regulatory Foresight, Regulatory Experimentation and Regulatory Learning
(2024)With the rapid pace of technological innovation, traditional methods of policy formation and legislating are becoming conspicuously anachronistic. The need for regulatory choices to be made to counter the deadening effect ... -
LIFE CYCLE ASSESSMENT (LCA) OF A NEWLY DESIGNED METAL ADDITIVE MANUFACTURING PROCESS: MAPS (METAL ADDITIVE MANUFACTURING USING POWDER SHEETS)
(2024)Additive manufacturing (AM), a transformative technology in modern manufacturing, offers design freedom and reduced material waste. However, understanding the environmental impacts of AM processes is imperative for sustainable ... -
Hemicellulose pyrolysis: mechanism and kinetics of functionalized xylopyranose
(2024)This work analyzes the thermochemical kinetic influence of the most prominent functionalizations of the β-d-xylopyranose motif, specifically 4-methoxy, 5-carboxyl, and 2-O-acetyl, regarding the pyrolytic depolymerization ... -
Klebsiella pneumoniae hijacks the Toll-IL-1R protein SARM1 in a type I IFN-dependent manner to antagonize host immunity.
(2022)Many bacterial pathogens antagonize host defense responses by translocating effector proteins into cells. It remains an open question how those pathogens not encoding effectors counteract anti-bacterial immunity. Here, we ... -
Dual NADPH oxidases DUOX1 and DUOX2 synthesize NAADP and are necessary for Ca2+ signaling during T cell activation
(2021)The formation of Ca2+ microdomains during T cell activation is initiated by the production of nicotinic acid adenine dinucleotide phosphate (NAADP) from its reduced form NAADPH. The reverse reaction—NAADP to NAADPH—is ... -
Cell Survival and Cytokine Release after Inflammasome Activation Is Regulated by the Toll-IL-1R Protein SARM
(2019)Assembly of inflammasomes after infection or injury leads to the release of interleukin-1β (IL-1β) and to pyroptosis. After inflammasome activation, cells either pyroptose or enter a hyperactivated state defined by IL-1β ... -
SARM: from immune regulator to cell executioner
(2019)SARM is the fifth and most conserved member of the Toll/Il-1 Receptor (TIR) adaptor family. However, unlike the other TIR adaptors, MyD88, Mal, TRIF and TRAM, SARM does not participate in transducing signals downstream of ... -
Poxviral protein E3-altered cytokine production reveals that DExD/H-box helicase 9 controls Toll-like receptor-stimulated immune responses.
(2018)Host pattern recognition receptors (PRRs) such as Toll-like receptors (TLRs) detect viruses and other pathogens, inducing production of cytokines that cause inflammation and mobilize cells to control infection. Vaccinia ... -
Learning Mixtures of Gaussian Processes through Random Projection
(2024)We propose an ensemble clustering framework to uncover latent cluster labels in functional data generated from a Gaussian process mixture. Our method exploits the fact that the projection coefficients of the functional ... -
Innate antiviral signalling in the central nervous system.
(2014)The innate immune system mediates protection against neurotropic viruses capable of infecting the central nervous system (CNS). Neurotropic viruses include herpes simplex virus (HSV), West Nile virus (WNV), rabies virus, ... -
The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling
(2006)Toll-like receptors discriminate between different pathogen-associated molecules and activate signaling cascades that lead to immune responses. The specificity of Toll-like receptor signaling occurs by means of adaptor ... -
CHCI-Mellon Crises of Democracy Global Humanities Institute Curriculum
(Consortium of Humanities Centers and Institutes, 2019)The Crises of Democracy Global Humanities Institute (GHI) was an 18-month project (2018-19) funded by the Consortium of Humanities and Centres institutes and the A.W. Mellon Foundation. The GHI brought together a consortium ... -
Sol–gel‑templated bioactive glass scaffold: a review
(2024)Purpose This review paper explores diverse synthesis strategies within the sol–gel technique for producing silicate bioglass with a focus on tailoring these materials for bone scaffold design. Method A comprehensive ... -
Melt electrowritten scaffold architectures to mimic tissue mechanics and guide neo-tissue orientation
(2024)All human tissues present with unique mechanical properties critical to their function. This is achieved in part through the specific architecture of the extracellular matrix (ECM) fibres within each tissue. An example of ... -
Development and physical characteristics of the Irish shelf-edge Macnas Mounds, Porcupine Seabight, NE Atlantic
(2024)Modern cold-water corals (CWCs) occur in a wide range of water depths, with Desmophyllum pertusum being one of the most common species. Pleistocene, Holocene, and modern coral mound formation by living CWC reefs have ... -
The vagina problem: a step too far in parent-child sex communication with young children
(2024)Parents describe a want for better sex education for their young children compared to their own myth and silence-led experiences while growing up. However, introducing the vagina has proved a challenging step too far for ... -
Augmenting K-means Clustering with Qualitative Data to Discover Engagement Patterns of Older Adults with Multimorbidity when using Digital Health Technologies: Findings from a Proof-of-Concept Trial
(2024)Background: Multiple chronic conditions (multimorbidity) are becoming more prevalent among aging populations. Digital health technologies have the potential to assist in the self-management of multimorbidity, improving the ... -
Signal-to-noise ratio of a mouse brain (13) C CryoProbe system in comparison with room temperature coils: spectroscopic phantom and in vivo results.
(2014)MRI and MRS in small rodents demand very high sensitivity. Cryogenic transmit/receive radiofrequency probes (CryoProbes) designed for (1) H MRI of mouse brain provide an attractive option for increasing the performance of ...