Browsing RSS Feeds by Sponsor "Higher Education Authority"
Now showing items 41-60 of 110
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Infection with a helminth parasite prevents experimental colitis via a macrophage-mediated mechanism.
(The American Association of Immunologists, 2007)The propensity of a range of parasitic helminths to stimulate a Th2 or regulatory cell-biased response has been proposed to reduce the severity of experimental inflammatory bowel disease. We examined whether infection with ... -
Intuitive Human Governance of Autonomic Pervasive Computing Environments
(IEEE, 2005)This paper proposes an intuitive configuration tool for autonomic pervasive computing systems. Specifically the paper presents a system for the inference of user task intentions from a variety of sensed information and ... -
Investigation of correlation between characteristics of Raman spectra and parameters of data-scattering obtained from phase coherence theory
(SPIE, 2005)The importance of sensitive monitoring of changes in Raman spectra in particular for microelectronic applications is discussed here. We explore the practicality of using a data-scattering method to analyse Raman spectra, ... -
Is 'Clinical' insight the same as 'Cognitive' insight in schizophrenia?
(Cambridge University Press, 2009)Poor insight is associated with impaired cognitive function in psychosis. Whether poor clinical insight overlaps with other aspects of self-awareness in schizophrenia, such as cognitive self-awareness, is unclear. We ... -
Lead identification of beta-lactam and related imine inhibitors of the molecular chaperone heat shock protein 90
(Elsevier, 2011)Heat shock protein 90 is an emerging target for oncology therapeutics. Inhibitors of this molecular chaperone, which is responsible for the maintenance of a number of oncogenic proteins, have shown promise in clinical ... -
Lead identification of conformationally restricted ?-lactam type combretastatin analogues: synthesis, antiproliferative activity and tubulin targeting effects
(Elsevier, 2010)The synthesis and study of the structure-activity relationships of a series of rigid analogues of combretastatin A-4 are described which contain the 1,4-diaryl-2-azetidinone (?-lactam) ring system in place of the usual ... -
Levels of detail for crowds and groups
(Blackwell, 2002)Work on levels of detail for human simulation has occurred mainly on a geometrical level, either by reducing the numbers of polygons representing a virtual human, or replacing them with a two-dimensional imposter. ... -
LibViz: Data Visualisation of the Old Library
(2009)The Old Library of Trinity College Dublin, built in 1732, is an internationally renowned research library. In recent decades it has also become a major tourist attraction in Dublin, with the display of the Book of Kells ... -
Loss of insight in frontotemporal dementia, corticobasal degeneration and progressive supranuclear palsy
(Oxford University Press, 2007)Loss of insight is one of the core features of frontal/behavioural variant frontotemporal dementia (FTD). FTD shares many clinical and pathological features with corticobasal degeneration (CBD) and progressive supranuclear ... -
Measuring network reliability by considering paradoxes
(National Academy of Sciences, 2009)Traditionally, game theoretic approaches to measuring transport network reliability have relied on the outcome of a game played between network users seeking to minimize their travel costs and an OD-specific demon that ... -
Measuring network reliability considering paradoxes: multiple network demon approach
(Transportation Research Board, 2009)Traditionally, game theoretic approaches to measuring transport network reliability have relied on the outcome of a game played between network users seeking to minimize their travel costs and an OD-specific demon that ... -
Mechanics applied to skeletal ontogeny and phylogeny
(Springer, 2002)The musculo-skeletal system serves the mechanical function of creating motion and transmitting loads. It is made up mainly of four components: bone, cartilage, muscle and fibrous connective tissue. These have evolved over ... -
Mental state decoding v. mental state reasoning as a mediator between cognitive and social function in psychosis
(The Royal College of Psychiatrists, 2008)Theory of mind deficits in schizophrenia have been parsed into mental state reasoning and mental state decoding components. We report that mental state decoding as measured by the `Eyes task? better predicted social function ... -
Mesons at high temperature in Nf = 2 QCD
(American Physical Society, 2006)We report first results for spectral functions of charmonium in 2-flavour QCD. The spectral functions are determined from vector and pseudoscalar correlators on a dynamical, anisotropic lattice. J/ and c are found ... -
A method to predict residues conferring functional differences between related proteins: application to MAP kinase pathways
(The Protein Society, 2000)Physicochemical properties are potentially useful in predicting functional differences between aligned protein subfamilies. We present a method that considers physicochemical properties from ancestral sequences predicted ... -
Microwave-assisted synthesis of icosahedral nickel nanocrystals
(2011)Nickel nanocrystals with icosahedral morphologies have been successfully synthesised using a microwave-assisted irradiation method. Nickel acetylacetonate was used as the metal precursor, while sodium formate and ... -
Mixed stochastic user equilibrium behavior under traveler information provision services with heterogeneous multiclass multicriteria decision making
(Taylor and Francis, 2009)This paper studies travellers? mixed stochastic user equilibrium (SUE) behaviour under traveller information provision services with heterogeneous multi-class multi-criteria decision making. A multi-class, multi-criteria ... -
Modelling damage growth and failure in elastic materials with random defect distributions
(Royal Irish Academy, 2004)Failure in materials under cyclic loading occurs by the growth and propagation of cracks. If they are sufficiently numerous, the cracks can be considered to be continuously distributed in the material. In this paper, a ... -
Modelling the interaction of catecholamines with the alpha1A Adrenoceptor- towards a ligand-induced receptor structure
(2005)Adrenoceptors are members of the important G protein coupled receptor family for which the detailed mechanism of activation remains unclear. In this study, we have combined docking and molecular dynamics simulations to ... -
Modulation of innate and acquired immune responses by Escherichia coli heat-labile toxin: distinct pro- and anti-inflammatory effects of the nontoxic AB complex and the enzyme activity
(The American Association of Immunologists, 2000)We have examined the roles of enzyme activity and the nontoxic AB complex of heat-labile toxin (LT) from Escherichia coli on its adjuvant and immunomodulatory properties. LTK63, an LT mutant that is completely devoid of ...