Huisgen-based conjugation of water-soluble porphyrins to deprotected sugars: Towards mild strategies for the labelling of glycans
Citation:
Giuntini, F., Bryden, F., Daly, R., Scanlan, E.M., Boyle, R.W., Huisgen-based conjugation of water-soluble porphyrins to deprotected sugars: Towards mild strategies for the labelling of glycans, Organic and Biomolecular Chemistry, 12, 8, 2014, 1203-1206Download Item:
Abstract:
Fully deprotected alkynyl-functionalised mono- and oligosaccharides undergo CuAAC-based conjugation with water-soluble porphyrin azides in aqueous environments. The mild reaction conditions are fully compatible with the presence of labile glycosidic bonds. This approach provides an ideal strategy to conjugate tetrapyrroles to complex carbohydrates
Sponsor
Grant Number
Engineering and Physical Sciences Research Council (EPSRC)
EP/ H000151
Author's Homepage:
http://people.tcd.ie/scanlaeDescription:
PUBLISHED
Author: SCANLAN, EOIN
Sponsor:
Engineering and Physical Sciences Research Council (EPSRC)Type of material:
Journal ArticleCollections
Series/Report no:
Organic and Biomolecular Chemistry12
8
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ChemistryDOI:
http://dx.doi.org/10.1039/c3ob42306aMetadata
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