Device for filamentous fungi growth monitoring using the multimodal frequency response of cantilevers.
Citation:
Maloney, N., Lukacs, G., Ball, S.L., Hegner, M., Device for filamentous fungi growth monitoring using the multimodal frequency response of cantilevers., The Review of scientific instruments, 85, 1, 2014, 015003Download Item:
Abstract:
Filamentous fungi cause opportunistic infections in hospital patients. A fast assay to detect viable
spores is of great interest. We present a device that is capable of monitoring fungi growth in real time
via the dynamic operation of cantilevers in an array. The ability to detect minute frequency shifts for
higher order flexural resonance modes is demonstrated using hydrogel functionalised cantilevers. The
use of higher order resonance modes sees the sensor dependent mass responsivity enhanced by a fac-
tor of 13 in comparison to measurements utilizing the fundamental resonance mode only. As a proof
of principle measurement,
Aspergillus niger
growth is monitored using the first two flexural resonance
modes. The detection of single spore growth within 10 h is reported for the first time. The ability to
detect and monitor the growth of single spores, within a small time frame, is advantageous in both
clinical and industrial settings
Sponsor
Grant Number
Science Foundation Ireland (SFI)
FI08/CE/I1432
Science Foundation Ireland (SFI)
09/IN.1/B2623
Author's Homepage:
http://people.tcd.ie/hegnermDescription:
PUBLISHED
Author: HEGNER, MARTIN
Sponsor:
Science Foundation Ireland (SFI)Science Foundation Ireland (SFI)
Type of material:
Journal ArticleCollections
Series/Report no:
The Review of scientific instruments85
1
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Full text availableKeywords:
Filamentous fungiDOI:
http://dx.doi.org/10.1063/1.4854655Metadata
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