Browsing Trinity College Dublin, the University of Dublin: Theses & Dissertations by Title
Now showing items 4598-4617 of 6412
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Redox cationic polymerisation
(Trinity College (Dublin, Ireland). School of Chemistry, 2011)The aim of this work is the development of an initiation chemistry that allows preparation of storage stable single-component epoxy compositions, which polymerize when contacted with metallic substrates, at ambient ... -
Reduced fetal movements in pregnancy: systematic reviews of the evidence and a case-control study of perinatal risk factors and outcomes
(Trinity College Dublin. School of Nursing & Midwifery. Discipline of Nursing, 2023)Background: The presence of fetal movements (FMs) is regarded as an indicator of fetal wellbeing during pregnancy. Conversely, maternal perception of reduced fetal movements (RFM) is considered a potential sign of a fetus ... -
Reducing overfitting in wrapper-based search
(Trinity College (Dublin, Ireland). School of Computer Science & Statistics, 2006)The benefits of wrapper-based techniques for feature selection are well established. However, it is acknowledged that overfitting can occur in feature selection using the wrapper method when there is a limited amount of ... -
Reducing reliance on private vehicles : a sustainability impact analysis of car sharing and ride sharing
(Trinity College (Dublin, Ireland). Department of Civil, Structural and Environmental Engineering, 2014)At the broadest level, the objective of this research work was to examine approaches to improving the sustainability of transport. This objective is accomplished by evaluating the impact of introducing two methods of ... -
Reducing Sedentary Behaviour in the Workplace: A Theory-led Multicomponent Intervention
(Trinity College Dublin. School of Medicine. Discipline of Public Health & Primary Care, 2021)There is strong evidence demonstrating that there is a relationship between greater time spent in sedentary behaviour (SB) and greater all-cause mortality, cardiovascular disease mortality and incidence, type 2 diabetes ... -
Reel trauma : contemporary screenings of Northern Irish conflict (1996-2005)
(Trinity College (Dublin, Ireland). Department of Film, 2007)Since the first IRA ceasefire in 1994, construction of discursive memory in Northern Ireland’s cultural spheres has politicised and sanitised historical trauma. This thesis identifies audio-visual culture as being exemplary ... -
Refinement of high-spatial resolution U-Pb geochronological methodologies
(Trinity College Dublin. School of Natural Sciences. Discipline of Geology, 2021)Zircon [ZrSiO4] is a naturally occurring mineral commonly used in geochronological, isotope and elemental geochemical studies. It can form as an accessory phase in a wide variety of magmatic and metamorphic conditions and ... -
Refining the psychometric properties of the Trinity Student Profile - A self-report measure of occupational performance difficulties within the student role in higher education.
(Trinity College Dublin. School of Medicine. Discipline of Occupational Therapy, 2024)Background: The Trinity Student Profile (TSP) is a self-report measure of occupational performance difficulties within the university student role and is based on the Person-Environment-Occupation Model. The tool was ... -
Reflections in a Panopticon : a reassessment of the music of Pierre Boulez in comparison with John Cage (1951-52), through analysis of their music and chart material
(Trinity College (Dublin, Ireland). Department of Music, 2009)This thesis reassesses works by Pierre Boulez, both individually, and in comparison with John Cage during the peak of their correspondence, 1951-52. Chart material for the works by Pierre Boulez— Structures, Book 1 and ... -
Reflections on the Financial and Ethical Implications of Music Generated by Artificial Intelligence
This work analyses the financial and ethical implications of music generated by Artificial Intelligence (AI). The primary concern of this work relates to issues of employment in the music industry challenged by AI ... -
Reforming the framework for employment litigation and dispute resolution in Ireland
(Trinity College (Dublin, Ireland). School of Law, 2013)This Research Project critically appraises the current dispute resolution mechanisms for employment law in Ireland. This exploration provides the basis for submissions to improve the overall service for workers, employers ... -
Regional-scale structure and dynamics of the crust, upper mantle and transition zone from waveform tomography with massive datasets
(Trinity College Dublin. School of Natural Sciences. Discipline of Geology, 2020)In the last decade, the number of seismic stations deployed globally increased dramatically, allowing to construct tomographic models with increasing resolution. Seismic data coverage however, is not homogeneous across the ... -
Regulating Crowdlending: A Critical Analysis of the European Union?s ECSPR
(Trinity College Dublin. School of Law. Discipline of Law, 2023)In 2020, the EU made its first foray into crowdlending regulation with the European Crowdfunding Service Providers for Business Regulation. This thesis explores whether the ECSPR has adequately responded to its regulatory ... -
Regulation of Antigen 43, a phase-variable autoaggregation factor of Escherichia coli
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Microbiology, 2003)The Antigen 43 protein (Ag43) of Escherichia coli, encoded by the agn43 gene, has previously been shown to be expressed in a phase-variable manner. A plasmidborne fusion of the agn43 regulatory region to the reporter gene ... -
Regulation of B cell function by human invariant natural killer T cells in health and autoimmune disease
(Trinity College (Dublin, Ireland). Department of Immunology, 2011)Invariant natural killer T (iNKT) cells are a subset of innate T lymphocytes that express a semi-invariant T cell receptor that recognises glycolipids presented on CD1d by antigen- presenting cells. They have the unique ... -
Regulation of bovine beta-defensin expression
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2017)Beta-defensins are a class of host defence peptides with antibacterial, antiviral and immunomodulatory roles. The bovine genome contains up to 57 putative beta-defensin genes in four syntenic clusters on different chromosomes. ... -
Regulation of cancer stem cell differentiation by genes and microRNAs
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy, 2012)Since the discovery of a stem cell phenotype in cancer, specific tumour cells with this phenotype, often called cancer stem cells (CSCs), are now widely accepted as the progenitors of oncogenesis, proliferation, treatment ... -
Regulation of expression of transcription factors nuclear factor-kappa B and early growth response-1 by Helicobacter pylori
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Pharmacology & Therapeutics, 2002)The Gram-negative bacterium Helicobacter pylori colonizes the human gastric epithelium and is a causative agent of peptic ulcer disease and gastric adenocarcinoma. Although H. pylori colonization is associated with gastric ... -
Regulation of innate and adaptive immune responses by synthetic and pathogen-derived immunomodulatory molecules
(Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2006)The development of new and improved vaccine formulations for human use requires the discovery of efficacious non-toxic adjuvants that enhance immune responses to poorly immunogenic purified native or recombinant antigens. ... -
Regulation of innate and adaptive immunity by the vaccine adjuvant alum
(Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2013)While many licensed vaccines consist of whole or inactivated pathogens, there is a move toward vaccines based on purified antigens which although safer are generally less immunogenic and therefore require adjuvants to ...