Browsing Trinity College Dublin, the University of Dublin: Theses & Dissertations by Title
Now showing items 6179-6198 of 6412
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Understanding lived experiences and contextual realities of Ebola outbreaks: A case studies approach in Western Uganda
(Trinity College Dublin. School of Medicine. Discipline of Public Health & Primary Care, 2018)Ebola Virus Disease (EVD) is caused by a highly infectious and fatal filovirus of zoonotic origin among human and primate populations on the African continent. EVD is classified as a potential ?public health emergency of ... -
Understanding stakeholders : towards a theory of responsiveness in organizations
(Trinity College (Dublin, Ireland). Trinity Business School, 2003)This study investigates the nature of responsiveness in organizations and its relation to dialogue as a reflective mode of conversation. Responsiveness as a theme emerged from the practical experience of the author in an ... -
Understanding the experience of loss, grief and bereavement for staff supporting persons with intellectual disability and dementia : a hermeneutic inquiry
(Trinity College (Dublin, Ireland). School of Nursing & Midwifery, 2012) -
Understanding the mechanism and functional effects of caspase-11 regulated nitric oxide production during inflammation and cancer
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2023)Inflammatory caspases are a group of cysteine aspartic proteinases essential for the inflammatory process, but when dysregulated are implicated in inflammatory diseases and cancer-associated chronic inflammatory events. ... -
Understanding the molecular interplay between bacterial pathogens and hosts : an evolutionary approach
(Trinity College (Dublin, Ireland). School of Genetics and Microbiology, 2012)The emergence of ecological adaptations is a fundamental conundrum in evolutionary biology. A magnificent and astonishing diversity of life forms occupy a myriad of ecological niches, from stable intra-cellular nutrition-rich ... -
Understanding the Role of IL-36 Family Cytokines in Paediatric IBD
(Trinity College Dublin. School of Medicine. Discipline of Immunology, 2021)Despite significant therapeutic advances, the global incidence of Inflammatory Bowel Diseases (IBD) continues to rise, with approximately 25% of these cases reported in childhood and adolescence. Aberrant CD4+ TΗ cell ... -
Understanding the role of low glass transition temperature excipients in the mitigation of amorphisation on mechanical processing
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2017)Commonly employed pharmaceutical processes such as milling, blending and compaction may unintentionally lead to the generation of amorphous regions or metastable polymorphic forms in crystalline active pharmaceutical ... -
Understanding the Role of MicroRNA-31 in Regulating Cellular Sensitivity to Chemoradiotherapy in Pancreatic Ductal Adenocarcinoma
(Trinity College Dublin. School of Medicine. Discipline of Surgery, 2023)Pancreatic adenocarcinoma (PDAC) is a lethal malignancy with a poor survival rate. One main challenge regarding PDAC is resistance to chemotherapy and radiotherapy. Therefore, there is an urgent requirement to characterise ... -
Understanding variation in ecology and physiology of marine migratory species.
(Trinity College Dublin. School of Natural Sciences. Discipline of Zoology, 2023)As the world faces the threats of multiple compounded and worsening crises, scientists are racing to gather the knowledge necessary to safeguard entire ecosystems and species. Technological advances are continuously ... -
Understanding volunteer community health worker motivation : a longitudinal cohort study in Sierra Leone
(Trinity College (Dublin, Ireland). Department of Public Health and Primary Care, 2014)Governments and non-profit organisations are once again turning to alternative cadres of health workers in an effort to accelerate health targets and address the severe global shortage of human resources for health. In low ... -
Undocumented migrants and the hegemonic ideology of the system of territorial states : a critical analysis of ideological contention in Irish Christians' moral imagination
(Irish School of Ecumenics, 2013)States respond punitively to those who cross their borders without authorisation. Consequently the human rights of undocumented migrants, often including the right to life itself, are systemically denied them. Every year, ... -
Undrained Triaxial Experimental Investigations and Hyperviscoplastic Modelling of Peat Materials
(Trinity College Dublin. School of Engineering. Disc of Civil Structural & Environmental Eng, 2017)This PhD research includes two parts, viz. experimental investigation on the undrained mechanical properties of undisturbed fibrous peat and a finite strain constitutive model within a thermodynamically consistent framework ... -
'Une paix precaire' Promoting local ownership using adaptive approaches. The case study of of North Kivu in the Democratic Republic of the Congo.
(Trinity College Dublin. School of Religion. Irish School of Ecumenics, 2023)In the early 2000s, almost ten years after its institutionalisation in 'Agenda for Peace' by Boutros Ghali (1992), peacebuilding entered into a crisis (Wiuff Moe and Stepputat 2018, 294) . The failure of ongoing and past ... -
Unearthing a forgotten Medieval Building Technique An Examination of Earth Mortared Stone Construction in Later medieval Ireland (1100-1600AD)
(Trinity College Dublin. School of Histories & Humanities. Discipline of History, 2018)In Ireland a largely missing domestic medieval settlement record stimulated archaeological research into understanding its absence. Regional field survey of standing later medieval buildings in north-west Ireland combined ... -
Uneven development and the third space in the urban system : evidence from Dublin
(Trinity College (Dublin, Ireland). Department of Geography, 2001)The objective of this study is to contribute to the understanding of urban social change through theoretical-empirical exploration of the third space in the city. To achieve this, the research examines some aspects of the ... -
Unexpected landscapes : literature and revolution in modern Ireland and Spain - 1913-39
(Trinity College (Dublin, Ireland). School of English, 2005)In this study I examine the inter-relationship between literature and revolution in modern Ireland and Spain. I concentrate on the period 1913 to 1923 in regard to Irish affairs, a decade that saw the re-emergence of the ... -
Unfettering constraint : deconstruction and the question of interpretation in the work of Georges Perec
(Trinity College (Dublin, Ireland). Department of French, 2002)The prolific body of work which Georges Perec produced in a remarkably short period of time is notoriously heterogeneous (from 1965, the date of publication of his first novel, Les Choses, until his death in 1982, his published ... -
Unholy images of corruption : the beast-man in the nineteenth-century novel
(Trinity College (Dublin, Ireland). School of English, 2005)This is not a thesis about beasts. Nor is it a thesis about men. It is, rather, a thesis about that indefinable and inhospitable distance that exists between the two, represented in popular fiction by the image of the ... -
UNICORN; Underlying mechanisms in Neonatal Immune Metabolic Dysregulation and Brain Injury
(Trinity College Dublin. School of Medicine. Discipline of Paediatrics, 2020)Introduction: Neonatal encephalopathy (NE) is a clinically defined syndrome of disturbed neurologic function, in the earliest days of life. NE has a multifactorial aetiology and causes significant mortality and neurological ... -
Unified pattern recognition and its application to handwriting recognition
(Trinity College (Dublin, Ireland). School of Computer Science & Statistics, 2002)The goal of this thesis is the design and the implementation of a visual pattern recognition system based on the analysis of fundamental principles of human perception. The system must simultaneously be psychologically ...