Browsing Trinity College Dublin Theses & Dissertations by Sponsor "Irish Cancer Society"
Now showing items 1-5 of 5
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Enhancing treatment response to neo-adjuvant radiation therapy in oesophageal cancer using novel dual action drugs targeting tumour energy metabolism and angiogenesis
(Trinity College Dublin. School of Medicine. Discipline of Surgery, 2019)Oesophageal cancer is an aggressive malignancy associated with a poor 5-year survival of <20%, accounting for over 400,000 deaths each year. The current standard of care for oesophageal adenocarcinoma (OAC) ... -
Examining the impact of a social prescribing service on the health & wellbeing of individuals living with and beyond cancer
(Trinity College Dublin. School of Medicine. Discipline of Occupational Therapy, 2020)Social prescribing is a community-based intervention that supports individuals with health needs and chronic conditions to access activities supports in their community. Due to medical improvements, more people than ever ... -
Investigation of the role of the complement system in the radioresistance of rectal cancer
(Trinity College Dublin. School of Medicine. Discipline of Surgery, 2023)Colorectal cancer (CRC) is the third most common cancer globally, accounting for approximately 10% of all cancer diagnoses. A third of CRCs occur in the rectum. The majority of CRCs are diagnosed at advanced stages and ... -
A promising set of candidate biomarkers of radioresistant prostate cancer
(Trinity College Dublin.School of Medicine.RADIATION THERAPY, 2016)Radiotherapy (RT) has a prominent role when used as a single modality or in combination with androgen deprivation therapy in the management of prostate cancer (CaP) patients. However, even with currently available high-dose ... -
Sterol Regulatory Element Binding Proteins; Central Metabolic Regulators of Natural Killer Cells
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2020)Natural killer (NK) cells have important functions in the immune response against pathogen- infected and transformed cells. NK cell metabolism is crucial for NK cell effector functions. In this study sterol regulatory ...