Browsing Trinity College Dublin Theses & Dissertations by Subject "T cells"
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Investigating the Immune System in Parkinson's Disease
(Trinity College Dublin. School of Medicine. Discipline of Physiology, 2024)In 1817 James Parkinson first described the symptoms of the Parkinson's disease (PD). It is the second most common neurodegenerative disease worldwide, and cases are rising exponentially. Characteristic hallmarks of PD ... -
Investigation of Staphylococcus aureus-induced immunosuppression during nasal colonisation and the implications for vaccine function
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2023)Staphylococcus aureus (S. aureus) is a major part of the natural human microbiome, primarily colonising the anterior nares. The overall aim of this project was to determine the impacts nasal colonisation has on local and ... -
Modulation of innate and adaptive immunity by Fasciola hepatica
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2018)Helminth parasites have developed highly effective mechanisms of immune subversion that helps prolong their survival in the host, resulting in the development of chronic infections. A bystander effect ...