Trinity College Dublin Theses & Dissertations: Recent submissions
Now showing items 1061-1080 of 7000
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From "Bench to Bedside": In-Silico Modelling to Inform the Assessment of Intervertebral Disc Cell-Based Therapies
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2023)Lower back pain is a major global socio-economic concern, with the primary cause believed to be degeneration of the intervertebral disc (IVD). While the spine field is filled with a growing body of basic research and many ... -
Interactions of Plasmonic and Dielectric Structures with 2D Materials
(Trinity College Dublin. School of Physics. Discipline of Physics, 2023)Three separate systems of nanoparticles coupled to two-dimensional materials are studied. Each system is investigated both experimentally and numerically with FDTD simulations. The first system involves a nanoparticle-on-mirror ... -
Synthetic Approaches Towards 3rd Generation, Light-Harvesting Metal-Organic Frameworks for Photo-Electrocatalytic Energy Conversions
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2023)Society?s increasing energy requirements as well as evident climate change problems present humanity with significant scientific challenges. Switching to more renewable energies sources such as the high density, carbon-free ... -
Memory and Displacement in Historical Fiction for Children about the Second World War, 2005?2021
(Trinity College Dublin. School of English. Discipline of English, 2023)This thesis examines the representation of memory and displacement in Anglophone historical fiction for children published between 2005 and 2021. It argues that memory is a significant aspect of how these texts ask the ... -
'Une paix precaire' Promoting local ownership using adaptive approaches. The case study of of North Kivu in the Democratic Republic of the Congo.
(Trinity College Dublin. School of Religion. Irish School of Ecumenics, 2023)In the early 2000s, almost ten years after its institutionalisation in 'Agenda for Peace' by Boutros Ghali (1992), peacebuilding entered into a crisis (Wiuff Moe and Stepputat 2018, 294) . The failure of ongoing and past ... -
The antiviral potential of itaconate and its derivative 4-Octyl itaconate against RNA viruses
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2023)Itaconate is a Krebs cycle derived metabolite which has been shown to have anti-inflammatory properties. This specially applies to derivatives of itaconate, notably the cell permeable analogue 4-octyl itaconate (4-OI) which ... -
Creating a Space for Recovery Oriented Organisational Culture: An Action Research Study
(Trinity College Dublin. School of Nursing & Midwifery. Discipline of Nursing, 2023)Aim: The focus of this study was to explore how the use of the Wellness Recovery Action Plan (WRAP) framework through an action research process might support an organisation to become more recovery-orientated. This was ... -
Heat Transfer in Open Quantum Systems
(Trinity College Dublin. School of Physics. Discipline of Physics, 2023)In most situations of practical interest, quantum systems are not isolated from their surroundings but are interacting with an environment. The importance of such situations has been highlighted, for example, in the fields ... -
Writing Ireland in the Latin chronicles and histories of early Plantagenet England
(Trinity College Dublin. School of Histories & Humanities. Discipline of History, 2023)This thesis offers a fresh examination of Latin writers' attitudes towards and depictions of Ireland, its affairs and its people in early Plantagenet England. Moving beyond the 'Geraldine paradigm' that has hitherto now ... -
Cobalt of the Tyrone Igneous Complex: geochemistry of mafic hosted sulphides and remobilisation
(Trinity College Dublin. School of Natural Sciences. Discipline of Geology, 2023)Primary sulphide mineralisation in mafic rocks and secondary remobilised sulphides contain significant cobalt and relate to early Palaeozoic ocean closure and arc-continent collision in the Irish Caledonian terrane. This ... -
Investigating the Signalling and Function of C5aR2
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2023)Complement component 5a receptor 2 (C5aR2) is an enigmatic receptor for anaphylatoxin C5a. It was initially thought to be a decoy receptor, competitively binding to C5a to negatively regulate C5aR1 signalling. However, ... -
Reading Forests, Seeing Trees: Visual Poetry with Neurohumanities
(Trinity College Dublin. School of English. Discipline of English, 2023)The new contexts of visual materiality engendered by the internet and digital age problematise traditional strategies of critically analysing experimental forms of poetry. By approaching poetry across history as a phenomenon ... -
The Akcal Epithermal Deposit: An Example of Low-Sulfidation Gold Mineralization in Western Turkey
(Trinity College Dublin. School of Natural Sciences. Discipline of Geology, 2023)The Akcal epithermal Au-Ag deposit is located on the Biga Peninsula, southwestern Turkey and is estimated to contain 32.5 million tonnes of mineralization at an average grade of 1.03 g/t Au, equivalent to 33.5 tonnes of ... -
Clinical Decision Support for the Assessment of Syncope and Falls: Novel Applications of Cerebral Perfusion Measurement and Big Data Analytics
(Trinity College Dublin. School of Medicine. CentreFor Medical Gerontology, 2023)Syncope, defined as a transient loss of consciousness due to cerebral hypoperfusion, is common in both young and old, with syncope an attributable cause of unexplained falls (UF) in older adults. Both syncope and falls ... -
Understanding the mechanism and functional effects of caspase-11 regulated nitric oxide production during inflammation and cancer
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2023)Inflammatory caspases are a group of cysteine aspartic proteinases essential for the inflammatory process, but when dysregulated are implicated in inflammatory diseases and cancer-associated chronic inflammatory events. ... -
Up-Rising: A Phonological and Phonetic Study of Intonation in Derry City English
(Trinity College Dublin. School of Linguistic Speech & Comm Sci. C.L.C.S., 2023)This thesis provides an account of the phonology and phonetics of intonation in Derry City English using the Autosegmental-Metrical (AM) framework (Ladd, 2008). It focuses on the phonological inventory and phonetic features ... -
Distributed Lag Regression Methods and Compartmental Models for Analysis of Disease Progression
(Trinity College Dublin. School of Computer Science & Statistics. Discipline of Statistics, 2023)ANCA vasculitis is an autoimmune disease characterised by relapses, or flares, that can have a severe detrimental impact on patient health. Flares can be prevented by suppressing the immune system but this exposes the ... -
Becoming-Sarmatian, becoming-Steppe. Deleuzoguattarian multiplicities / thresholds / potentialities and the art-work of Marek Konieczny
(Trinity College (Dublin, Ireland). Department of Russian & Slavonic Studies, 2016)The present dissertation maps out the artistic practices of the Polish neo-avant-garde artist Marek Konieczny between 1962 and 1986. Marek Konieczny is a Warsaw-based artist who since the late 1960s has embarked on a ... -
Topics in Urban and Transport Economics
(Trinity College Dublin. School of Social Sciences & Philosophy. Discipline of Economics, 2023)This dissertation consists of three essays at the intersection of urban and transport economics. While they do not use common data or methods, they all tackle fundamental issues concerning the effects of transport on ... -
Mucosal Associated Invariant T Cells and Insulin Resistance in Hidradenitis Suppurativa
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2023)Hidradenitis suppurativa (HS) is a chronic, inflammatory skin disease characterised by recurrent painful nodules, abscesses and draining sinus tracts. There is a paucity of effective treatments and it severely impairs ...
