Trinity College Dublin Theses & Dissertations: Recent submissions
Now showing items 1361-1380 of 7000
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Hungry for More: Measuring Metabolomic Responses in ANCA-Activated Monocytes
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2022)Immunometabolism examines the links between immune cell function and their metabolism. Advances in liquid chromatography mass spectrometry (LC-MS) technologies have uncovered unique insights into cellular metabolomics. ... -
Modelling techniques to inform the design of sub-wavelength periodic acoustic structures
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2022)Minimising the environmental impact of aircraft noise and ensuring the sustainability of air travel in the future is crucial for the development of the industry. The ad- vancement in additive manufacturing paves the way ... -
3D Bioprinted Cartilaginous Templates as Developmentally Inspired Implants for Large Bone Defect Regeneration
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2022)Whilst bone possesses an inherent capacity for regeneration, defects above a critical size cannot heal on their own. Damaged or diseased bone can be treated using autografts or a range of different bone grafting biomaterials, ... -
Implementing internet-delivered cognitive behavioural therapy for depression and anxiety in routine care: an exploratory study of implementation
(Trinity College Dublin. School of Psychology. Discipline of Psychology, 2022)Internet-delivered cognitive behaviour therapy interventions (iCBT) for depression and anxiety have proven their clinical utility through a number of controlled trials, but few studies have been conducted in routine care ... -
Evaluation of an in-house six-well screening plate as a means of detecting phenotypic triazole resistance in St. James's Hospital, Dublin with emphasis on Aspergillus fumigatus
(Trinity College Dublin. School of Medicine. Discipline of Clinical Microbiology, 2022)Aspergillus fumigatus is a ubiquitous saprophytic mould fungus found in nature. This fungus is present in the air, in soil, in foliage in our food stock and on inanimate surfaces. For healthy individuals, A. fumigatus poses ... -
Spectral Gamma Ray (SGR) Analysis of Sedimentary Environments in Early Continental Rift Basins: Implications for Petroleum Exploration
(Trinity College Dublin. School of Natural Sciences. Discipline of Geology, 2022)Continental rift basins are structures of global geoscientific significance, as they hold over 30% of the world?s giant oil fields and serve as modern day examples of unique biodiversity sites, typically operating as ... -
A Case Study Analysis of Irish Primary Schools Principals:Perspectives of and Experiences in Their Role
(Trinity College Dublin. School of Education. Discipline of Education, 2022)Summary Research consistently concludes that school leadership impacts both directly and indirectly on a myriad of school factors (Grisson et al., 2021; Leithwood et al., 2020; Day et al., 2016; Harris and Jones, 2020). ... -
Population Ecology from Local to Global Scales: a case study using Plantago lanceolata
(Trinity College Dublin. School of Natural Sciences. Discipline of Zoology, 2022)This thesis investigated approaches to infer on demographic processes across varying scales and environmental gradients, pulling information from multiple sources. I used the model organism Plantago lanceolata. This perennial ... -
Methods Development for the Synthesis of Biologically Relevant Porphyrins and Porphyrin Rigid Linker Arrays
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2022)This research focuses on two main aspects: The synthesis of new derivatives of naturally occurring porphyrins and the preparation of non-natural chromophore-rigid linker conjugates as potential bioisosteres and mimics of ... -
Cost-effective deployment strategies for the rural FTTH roll-out
(Trinity College Dublin. School of Computer Science & Statistics. Discipline of Computer Science, 2022)The main topic of this dissertation revolves around the problem of ru- ral FTTH service roll-out. The problem has become topical worldwide, typically in the countries with rural populations scattered around. Never- theless, ... -
The Decline of the aristocracy and second Duke of Westminster 1900-40.
(Trinity College Dublin. School of Histories & Humanities. Discipline of History, 2022)The title of my thesis is 'The Decline of the aristocracy and second Duke of Westminster 1900-40'. As my subject I have used the second Duke of Westminster to examine how the aristocracy reacted to the social, economic and ... -
Growing up deaf in Ireland
(Trinity College (Dublin, Ireland). Centre for Language and Communication Studies, 1997)The aim of this dissertation is to describe my own linguistic experience at school and by doing so provide a general understanding of the linguistic experience of Irish Deaf children during the period that oral education ... -
Letter writing in seventh-century Europe: the case of Columbanus's Epistulae
(Trinity College Dublin. School of Histories & Humanities. Discipline of History, 2022)The goal of this project is to present a comprehensive commentary to the collection of five Latin letters attributed to the Irish abbot and monastic founder Columbanus (c. 550-615). He was the first Irish man of letters ... -
Protocol development and feasibility study of an evidence-based online pregnancy yoga programme for stress, anxiety and fear of childbirth
(Trinity College Dublin. School of Nursing & Midwifery. Discipline of Nursing, 2022)Background: The importance of maintaining a healthy lifestyle and positive mental health during pregnancy are well publicised. Maternal stress, anxiety and fear of childbirth in pregnancy have been associated with an ... -
The role of dietary fat in anti-tumour immunity
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2022)Obesity increases the risk of many cancers and impairs immunosurveillance. However, little is known about whether the type of dietary fat affects tumour growth and anti-tumour immune responses. Here, we show that a ... -
A History and Phonological Study of the Native Modern Irish of Co. Wexford
(Trinity College Dublin. School of Lang, Lit. & Cultural Studies. Discipline of Irish, 2022)This thesis uses historical and placename evidence to better understand the displacement of native Irish from Co. Wexford, from the introduction of Norse in the 9th century, to the many stages of introduction of English ... -
The role of the biophysical cues on the initiation, progression and maintenance of a chondrogenic phenotype in human stem cells
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2022)Articular Cartilage Tissue Engineering (AC TE) is a promising strategy for the treatment of small cartilage defects, however complete mimicry of the native tissue remains a significant challenge. Mechanical cues like dynamic ... -
Ultrafast Optical Nonlinearity of Liquid Phase Exfoliated Pdse2 Nanosheets.
(Trinity College Dublin. School of Physics. Discipline of Physics, 2022)In recent years, the study of condensed matter and optical physics has resulted in increasing technological progress, and this study may be credited with a significant portion of current scientific research and technical ... -
Hauntologies of Domestic Space in Contemporary Women's Writing, 1985-2015: Alice Munro, Lorrie Moore, and Anne Enright.
(Trinity College Dublin. School of English. Discipline of English, 2022)This dissertation utilises a hauntological understanding of domestic space in order to examine spectral presences in the fiction of three contemporary women writers, Alice Munro, Lorrie Moore, and Anne Enright, focusing ... -
Tumour microenvironment, extracellular vesicles and their effect on prostate cancer progression and docetaxel resistance
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2022)Prostate cancer is the fourth most common cancer in Europe and the third leading cause of death in males. The standard of care as initial treatment for prostate cancer is, typically, androgen-deprivation therapy. Although ...
