Trinity College Dublin Theses & Dissertations: Recent submissions
Now showing items 1421-1440 of 7000
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Cyclosporine A modulates CD103+ DC responses to fungal PAMPs
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2022)Cyclosporine A (CsA) is an immunosuppressant that protects against inflammatory diseases and graft rejection. Despite its strong efficacy, one side-effect of CsA is an increased risk of fungal infection. To minimise this, ... -
Game-Based Learning of Data Structures Based onAnalogies: Learning Gains andIntrinsic Motivation in Higher Education Environments
(Trinity College Dublin. School of Computer Science & Statistics. Discipline of Computer Science, 2022)Many researchers have considered video games as effective learning tools. According to them, video games can increase intrinsic motivation and promote active learning. However, video games are a flexible medium, and they ... -
LOFAR Observations of Shocks in the Solar Corona
(Trinity College Dublin. School of Physics. Discipline of Physics, 2022)The Sun can produce large-scale energetic events such as solar flares and coronal mass ejections, which can excite shock waves that propagate from the low solar atmosphere into interplanetary space. Such shocks can result ... -
Cerebral Blood Flow and Cerebrovascular Reactivity Measurement using Arterial Spin Labeling MRI: Data from The Irish Longitudinal Study on Ageing (TILDA)
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2022)Background: Cerebral blood flow (CBF) and cerebrovascular reactivity (CVR) are important measures of cerebrovascular integrity and may provide an imaging biomarker for the early detection of diseases such as dementia and ... -
Automatic program generation for convolutional neural networks on resource constrained devices
(Trinity College Dublin. School of Computer Science & Statistics. Discipline of Computer Science, 2022)Convolutional Neural Networks (CNNs) are both arithmetically and memory intensive when performing inference. This is a problem when executing CNNs on resource constrained machines, such as small embedded devices. This ... -
Beckett's and Murakami's 'Vaguened' Worlds
(Trinity College Dublin. School of English. Discipline of English, 2022)On the first page of the first Happy Days typescript, Samuel Beckett wrote the self-instruction vaguen it : the obscuring and occasional erasure of contextual markers occurs frequently throughout his body of work. It is ... -
Characterisation and Manipulation of Transition Metal Dichalcogenides via Atomic Force Microscopy
(Trinity College Dublin. School of Physics. Discipline of Physics, 2022)Scanning probe microscopy (SPM) has revolutionised nanotechnology and allowed the study and manipulation of materials at the nanoscale, making it ideal for the study of solid-state physics and semiconductor technologies. ... -
Investigation of Particulate Phosphorus Mobilised by Run-offin Small Agricultural Catchments
(Trinity College Dublin. School of Engineering. Disc of Civil Structural & Environmental Eng, 2022)Research carried out in this work has contributed valuable insights and new findings into the impact of particulate phosphorus (PP) associated with fluvial suspended sediments, in terms of its sources and speciation dynamics ... -
Deep Interactive Image Matting
(Trinity College Dublin. School of Engineering. Discipline of Electronic & Elect. Engineering, 2022)Image Matting for Compositing is the cutting of an object from an image for background replacement. It is an interactive process fundamental to image editing. Useful matting algorithms both reduce the amount of interaction ... -
Guanidine based derivatives as potential anti-infective agents: Tackling protozoal diseases and Mycobacterium tuberculosis
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2022)Infectious diseases caused by microorganisms of the genus Trypanosoma (Human African Trypanomiasis-HAT), Leishmania (Leishmaniasis), Plasmodium (Malaria) and Mycobacterium (Tuberculosis) cause some of the deadliest human ... -
Does the future of epilepsy care lie in eHealth? An examination of attitudes and behaviours towards epilepsy self-management and eHealth from the perspectives of people with epilepsy, their carers and healthcare providers
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The Right to Religious Freedom under International Human Rights Law and Islamic Jurisprudence: A Re-Interpretation
(Trinity College Dublin. School of Law. Discipline of Law, 2022)This thesis examines the Right to Freedom of Religion under the International Human Rights legal regime and Islamic jurisprudence. It does so in order to highlight the shortcomings of the way this right is interpreted under ... -
Investigating the applicability of immune checkpoint blockade in upper gastrointestinal cancers
(Trinity College Dublin. School of Medicine. Discipline of Surgery, 2022)Oesophagogastric junctional adenocarcinoma (OGJ) is an aggressive malignancy with a high propensity to metastasise. Response rates to first-line chemo(radio)therapy regimens remain poor therefore, better treatment options ... -
Behind 'The Last Door': Prison Managers' Experiences of Accountability and Oversight
(Trinity College Dublin. School of Law. Discipline of Law, 2022)Prison oversight is regarded by penology scholars as an essential means by which human rights and humane conditions in prison are upheld. However, despite significant growth in the number of oversight bodies in Ireland, ... -
'Our Modern Hope': An Analysis of Unorthodox Religion in the Writings of W. B. Yeats and Juan Ramón Jiménez
(Trinity College Dublin. School of English. Discipline of English, 2022)The theological modernist movement articulated many of the issues that literary modernism went on to develop, particularly in relation to religion and the individual s place within it. Theological modernism had a profound ... -
Vehicles of Meaning: Ships, Materiality, and the Boundaries of the Iliad
(Trinity College Dublin. School of Histories & Humanities. Discipline of Classics, 2022)Ships are the most prominent material objects in the world of epic and the lemma ship (νηῦς) is the one of the most common substantives in the Iliad. Despite this, there has never been a sustained account of what ships do ... -
An Investigation into the leading factors that affect teachers' decision-making towards curricula change in Irish post-primary schools
(Trinity College Dublin. School of Education. Discipline of Education, 2022)In recent years there has been an international resurgence in curriculum change. Intercontinental influences such as globalisation and international testing have resulted in a transformation of traditional educational ... -
India's Mental Healthcare Act, 2017 Evaluation of the Act, its Context and Initial Implementation
(Trinity College Dublin. School of Medicine. Discipline of Psychiatry, 2022)The United Nations has initiated a paradigmatic shift in mental healthcare through the United Nations Convention on the Rights of Persons with Disabilities (CRPD), in addition to this the WHO has identified legislation as ... -
Examining the Generalisability of `Social Drama' for Young People with Autism Spectrum Disorders to Natural Environments
(Trinity College Dublin. School of Education. Discipline of Education, 2022)Autism Spectrum Disorders (ASD) are becoming more prevalent in Ireland, with literature positing that a common challenge for those with ASD is generalising social skills from intervention settings to natural environments. ... -
Modulation of prostaglandin production by indole-3-pyruvate and 4-octyl itaconate in proinflammatory
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2022)The recent surge in immunometabolism research has revealed how specific changes in the level of metabolites can affect the immune response. One important feature of the immune response is the production of a class of lipid ...
