Trinity College Dublin Theses & Dissertations: Recent submissions
Now showing items 81-100 of 7000
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Mechano-immunomodulatory strategies for bone regeneration
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2025)Every 3 seconds a person suffers from an osteoporosis (OP) related bone fracture, resulting in significant disability, loss of independence, and early mortality. This systemic skeletal disease is characterised by low bone ... -
Collective Victimhood Narratives in Legislative Speeches from the United States and Northern Ireland
(Trinity College Dublin. School of Social Sciences & Philosophy. Discipline of Political Science, 2025)In this thesis, I examine the use of victimhood narratives by legislators in the United States Congress and the Northern Ireland Assembly. Collective victimhood is a form of highly emotive and moral rhetoric which depicts ... -
Investigating the role of miRNAs in the resistance of oesophago-gastric cancer to cytotoxic therapy
(Trinity College Dublin. School of Medicine. Discipline of Surgery, 2025)Oesophago-gastric cancers are two of the most commonly diagnosed cancers and the majority of oesophageal adenocarcinoma (OAC) and gastric adenocarcinoma (GAC) patients are diagnosed at a late stage. The standard of care ... -
Identifying and addressing uncertainties regarding the tapering of psychiatric medications
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, 2025)Background: There is a cohort of individuals looking to discontinue use of psychiatric medication. Tapering is the recommended approach for reducing and/or stopping the use of psychiatric medication. This involves ... -
The Oral Health of the Irish Army
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2025)Background Dental services are provided in the Army for operational reasons as a means of collecting dental forensic charting and reducing the likelihood of a dental emergency. Recent data reporting the oral health of ... -
Molecular and clinical aspects of blood-brain barrier dysfunction in traumatic brain injury
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2025)Traumatic brain injury (TBI) is a leading cause of death and disability worldwide. TBI ranges from mild to severe, with concussion being considered a form of mild TBI (mTBI). Long-term issues, such as cognitive impairment ... -
Characterisation of the T cell response during Staphylococcus aureus nasal colonisation
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2025)While Staphylococcus aureus is primarily recognised as an invasive pathogen, it is also an important component of the normal human microbiome, persistently colonising the nasal tissue (NT) of a significant proportion of ... -
Searching for late-time interaction between Type Ia supernovae and distant circumstellar material using the Zwicky Transient Facility
(Trinity College Dublin. School of Physics. Discipline of Physics, 2025)The nature of the progenitor systems and explosion mechanisms that give rise to Type Ia supernovae (SNe Ia) is still debated. In rare cases the ejecta interact with circumstellar material (CSM) that was ejected from the ... -
Novel Non-Invasive Investigation of Spinal Cord Electrical Activity in Health and Neurodegeneration
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2025)The spinal cord (SC) extends from the lower end of the medulla oblongata to the lumbar region and is divided into five segments: cervical, thoracic, lumbar, sacral, and coccygeal. The spinal cord, as part of the central ... -
Sedimentary and foliar mercury sequestrations in contemporary and palaeo-environments, and the establishment of a new leaf-based atmospheric mercury proxy
(Trinity College Dublin. School of Natural Sciences. Discipline of Geology, 2025)Gaseous emissions from Phanerozoic large igneous province (LIP) emplacements have been implicated as instigators of global carbon cycle perturbations and associated global change and mass extinction events. However, ... -
A Comparative Evaluation of Two Delivery Methods for a Work Focused Fatigue Management Intervention for Individuals with Inflammatory Arthritis
(Trinity College Dublin. School of Medicine. Discipline of Occupational Therapy, 2025)ABSTRACT Background: Inflammatory Arthritis (IA) often leads to early work disability, impacting employment and causing socio-economic challenges. Fatigue is a major symptom that affects productivity and increases ... -
Investigation of an Essential Oil Blend as a Complementary Therapy to Reduce Stress and Aid Relaxation.
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2025)Aromatherapy is the therapeutic use of essential oils extracted from plants to support health and wellbeing. In recent years, the practice of aromatherapy, has been increasingly integrated into clinical settings to support ... -
The Theology of Teresa Deevy, Exhuming the Playwright's Life and Later Works
(Trinity College Dublin. School of English. Discipline of English, 2024)In the first half of the 1930s Teresa Deevy, a deaf writer from Waterford, was one of the most prolific and acclaimed woman playwrights in the world. At the height of her career, Deevy was a favourite of the Abbey Theatre ... -
Exact Conditions in Density Functional Theory and their application to Hubbard type Corrective Functionals
(Trinity College Dublin. School of Physics. Discipline of Physics, Trinity College Dublin, School of Physics, 2025)The work of this thesis falls within the topic of Kohn Sham (KS) and Generalised Kohn Sham (GKS) theory, the practical implementation of which are the most popular tools for predicting the electronic properties of atoms, ... -
Une Certaine Idée de l'Algérie: The Nationalist Right, the Army and the Ideological Fight for French Algeria 1958-1962
(Trinity College Dublin. School of Lang, Lit. & Cultural Studies. Discipline of French, 2025)The study of the defenders of French Algeria is typically centred around either a narrative of military praetorianism in three acts (13 May 1958, semaine des barricades, and putsch des généraux), or as a prologue to studies ... -
Design, Synthesis, and Photophysical and Biological Studies of Naphthalimide Bioconjugates for Medicinal and Materials Applications
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, School of Chemistry, 2025)This thesis presents significant advancements in the synthesis, characterization, and use of Naphthalimide (Nap) based biological relevant compounds for bioimaging and therapeutic applications. Extensive photophysical ... -
The Effects of Immunoregulatory Therapies on Human Macrophage Function and Metabolism: Implications for Mycobacterial Infections and Diseases
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2025)Tuberculosis (TB), an endemic infecƟous disease caused by Mycobacterium tuberculosis (Mtb) is a huge burden globally. Dexamethasone is a potent long-acƟng syntheƟc glucocorƟcoid (GC) and presently, the role of GC as an ... -
Phytochemical Analysis and Anti-Inflammatory Activity of Capparis cartilaginea Decne. from Saudi Arabia: An Ethnopharmacological Study
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2025)Background: Capparis cartilaginea (C. cartilaginea) is a species belonging to the Capparaceae family, which is known for its various traditional medicinal uses. In Saudi Arabia, the leaves and roots of C. cartilaginea are ... -
Spanish cinema and the rise of the auteur : the case of Isabel Coixet
(Trinity College (Dublin, Ireland). Department of Hispanic Studies, 2015)This thesis builds on and contributes to work in the field of film authorship and auteurism, critically considering Spanish director Isabel Coixet as a prime example of a contemporary, self-styled auteur. Heavily influenced ... -
The impact on Ireland of French maritime warfare, 1692-1713
(Trinity College (Dublin, Ireland). Department of History, 2014)Historical research on early-modern Ireland bypassed the period between 1691 and 1770 for a long time. Yet this period saw the beginnings of long-term economic growth that eventually changed Irish society drastically. ...
