Trinity College Dublin Theses & Dissertations: Recent submissions
Now showing items 941-960 of 7000
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Exploring efficient methods for precision QCD calculations on the lattice
(Trinity College Dublin. School of Mathematics. Discipline of Pure & Applied Mathematics, 2023)We study a new technique for stochastic noise reduction in the calculation of propagators by implementing it in OpenQ*D for two ensembles with O(a) improved Wilson fermion ac- tion, with periodic boundary conditions and ... -
The role of the Locus Coeruleus-Noradrenergic system integrity in the main Dementia modifiable risk factors: a comparative approach linking neuropsychological measures to biological and lifestyle indices
(Trinity College Dublin. School of Psychology. Discipline of Psychology, 2023)Dementia etiopathogenesis is characterised by a plethora of heterogeneous and diverse factors, which contribute to delay the definition of effective treatments and preventing strategies. Growing evidence identifies in the ... -
Measuring physical function in Amyotrophic Lateral Sclerosis: Novel solutions to an old problem
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2023)Sensitive, objective outcome measures are essential for tracking clinical severity in neurodegenerative conditions such as Amyotrophic Lateral Sclerosis or Parkinson’s Disease. The current ‘gold standard’ multi-item rating ... -
Structure and evolution of the upper mantle of the Australian Plate and North Atlantic Ocean from waveform tomography
(Trinity College Dublin. School of Natural Sciences. Discipline of Geology, 2023)With the expansion of regional and global seismic networks and the advancing of tomographic techniques, tomography models are able to reveal the heterogeneities in the Earth's interior with an increasing amount of detail. ... -
Investigation of Staphylococcus aureus-induced immunosuppression during nasal colonisation and the implications for vaccine function
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2023)Staphylococcus aureus (S. aureus) is a major part of the natural human microbiome, primarily colonising the anterior nares. The overall aim of this project was to determine the impacts nasal colonisation has on local and ... -
The Memory of the Norse in Ireland in Middle Irish Dynastic Narratives
(Trinity College Dublin. School of Histories & Humanities. Discipline of History, 2023)Three dynastic propaganda narratives written to valorise the ancestor of a Gaelic patron feature a complicated career against, and at times alongside, Norse speakers operating in Ireland. These are the Cerball of Osraige ... -
An Analysis of Foreign Direct Investment in Indonesia from 1980 -2019
(Trinity College Dublin. School of Business. Discipline of Business & Administrative Studies, 2023)Foreign Direct Investment (FDI) has been the focus of research in the field of International Business (IB). Despite the significant development of previous studies on FDI and its role in a country, particularly in emerging ... -
The Spaces Between Us: A Qualitative Exploratory Study of Perinatal Death, Burial & Bereavement in 20th century Ireland
(Trinity College Dublin. School of Nursing & Midwifery. Discipline of Nursing, 2023)This thesis showcases an interdisciplinary and comprehensive exploration of perinatal death in Ireland through the nineteenth and twentieth centuries. Employing a social constructionist approach, this study questions the ... -
Coercion and Involuntary Care: A Study of Involuntary and Voluntary Psychiatry Inpatients in Dublin
(Trinity College Dublin. School of Medicine. Discipline of Psychiatry, 2023)Involuntary care is a feature of mental health services around the world. In addition to involuntary admission and treatment, specific coercive or restrictive practices including seclusion and physical restraint occur in ... -
Essays in Political Economics
(Trinity College Dublin. School of Social Sciences & Philosophy. Discipline of Economics, 2023)This dissertation consists of three essays on political economics. First, it studies how changes in the electoral design affect politicians and voters alike. Second, it studies the impact of criminal organisations on both ... -
A Longitudinal Study of the Evolution of Neuropsychological Change in Amyotrophic Lateral Sclerosis: The Incidence, Nature and Progression of Language Impairment.
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2020)Background: Amyotrophic Lateral Sclerosis is a multi-system disease that also affects cognition and behaviour. Cognitive change in ALS manifests most commonly as executive dysfunction. Although changes in language function ... -
Using the ACE survey to inform service development in a social care organisation: A case study
(Trinity College Dublin. School of Social Work & Social Policy. Discipline of Social Studies, 2023)In recent years implementation of the Adverse Childhood Experience (ACE) survey within social care organisations has steadily increased. Despite the sustained implementation, there is limited research on how and if ACE ... -
Alcohol use and alcohol-related harms: Exploring risk and protective factors among young people living in urban disadvantage
(Trinity College Dublin. School of Nursing & Midwifery. Discipline of Nursing, 2023)The aim of the research is to explore the potential risk and protective factors associated with alcohol use, binge drinking and harmful consequences of alcohol use, under the broad domains of health-related quality of life, ... -
Hannah Arendt's Unwritten Theory of Political Judgment
(Trinity College Dublin. School of Social Sciences & Philosophy. Discipline of Philosophy, 2023)This project develops a new reading of Hannah Arendt’s interpretation of Immanuel Kant’s aesthetic reflective judgment. The aim of this project is to justify Arendt’s claim that she brings Kant’s unwritten political ... -
Exploring the influence of obesity, fatty acids, and current treatment modalities on the immune-metabolic profiles of adipose tissue in oesophageal cancer
(Trinity College Dublin. School of Medicine. Discipline of Surgery, 2023)Oesophageal adenocarcinoma (OAC) is a poor prognosis cancer with limited response rates to current standard of care treatments including chemotherapy and chemoradiotherapy. OAC has one of the strongest associations with ... -
Probabilistic Behavioural Modelling of Non-Linear Devices
(Trinity College Dublin. School of Engineering. Discipline of Electronic & Elect. Engineering, 2023)Behavioural device models are black-box models which depend only on measured data and are independent of the underlying physics behind the working of the device. Behavioural device models are widely used to model non-linear ... -
Deciphering the interplay of extracellular vesicles and drug resistance in HER2-positive breast cancer: insights, biomarkers and therapeutic implications
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2023)According to a World Health Organisation (WHO) report on 3rd March 2021, breast cancer is the most common form of cancer in the world and the leading cause of cancer death among females. In 2020, 2.26 million newly breast ... -
Oxysterols - new players in regulation of Natural Killer cells
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2023)Natural Killer (NK) cells are cytotoxic, innate lymphocytes that play a crucial role in mediating viral and tumour responses as well as supporting tissue homeostasis. Due to their fast acting immune response independent ... -
Integrative multi-omic analytics for the early detection of pancreatic cancer
(Trinity College Dublin. School of Medicine. Discipline of Surgery, 2023)Pancreatic cancer (PC) has the lowest 5-year survival rate of any cancer, at just 12% in 2023. The poor survival rates observed in this cancer are the result of an accumulation of shortcomings and gaps in many aspects of ... -
Control of a Dynamic Wheeled-legged Robot Powered by Electric-Pneumatic Actuators
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2023)The implementation of wheels on the end distal of a mobile robot's leg is a design approach that is gaining increasing popularity as it enables improved energy efficiency, stability and adaptive locomotion strategies in ...
