Trinity College Dublin Theses & Dissertations: Recent submissions
Now showing items 981-1000 of 7000
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Investigation of the role of the complement system in the radioresistance of rectal cancer
(Trinity College Dublin. School of Medicine. Discipline of Surgery, 2023)Colorectal cancer (CRC) is the third most common cancer globally, accounting for approximately 10% of all cancer diagnoses. A third of CRCs occur in the rectum. The majority of CRCs are diagnosed at advanced stages and ... -
Connectivity of the Executive Control Network and Its Relation to Function in Adults and Infants
(Trinity College Dublin. School of Psychology. Discipline of Psychology, 2023)The executive control network (ECN) is critical for effective, organized behavior. But what mechanisms allow it to play this core role in higher cognition? An important property of the ECN is thought to be its connectivity ... -
Essays in Development Economics
(Trinity College Dublin. School of Social Sciences & Philosophy. Discipline of Economics, 2023)This thesis is a collection of three essays in Development Economics. In 2022, 685 million people globally lived in extreme poverty, the rate of decline in poverty is at a paltry rate of 2 percent per year (World bank, ... -
Impact of Chronic Pain on Adolescents' School Functioning and Pain Management Interventions in the School Setting
(Trinity College Dublin. School of Nursing & Midwifery. Discipline of Nursing, 2023)Background: Chronic pain is a widespread issue in children's health that has a widespread impact on daily activities including participation in school settings. Thus, effective pain management has been emphasised to lessen ... -
Approaches to Drying Hydrated Active Pharmaceutical Ingredients (APIs).
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2023)This project aims to develop a drying protocol that removes unwanted moisture from hydrated APIs while preserving water of hydration. Hydrate forms of model compounds, carbamazepine and theophylline, were generated with ... -
Essays in financial and behavioural economics
(Trinity College Dublin. School of Social Sciences & Philosophy. Discipline of Economics, 2023)This thesis comprises three essays. The first two essays (Chapters 2 and 3) describe randomised controlled trials which experimentally test interventions to arm consumers with informational tools to navigate the promise ... -
Identification of predictors of gait speeds in The Irish Longitudinal Study on Ageing using automated feature selection and explainable machine learning
(Trinity College Dublin. School of Medicine. Discipline of Medical Gerontology, 2023)This work reports the novel application of automated feature selection and explainable machine learning to identify and compare, in participants aged 50 years or over from wave 3 of The Irish Longitudinal Study on Ageing ... -
Oppian's Piscine Dialectic
(Trinity College Dublin. School of Histories & Humanities. Discipline of Classics, 2023)The central premise of this study is that Oppian?s Halieutica is a poem that poses questions and offers a variety of perspectives on issues such as the place of humans in the natural world, the cognitive abilities of ... -
Impact of School Nurse Asthma Education Programme on School Nurses' Asthma Knowledge and Self-Efficacy Levels: A Quasi-Experimental Study
(Trinity College Dublin. School of Nursing & Midwifery. Discipline of Nursing, 2023)Background Asthma is a prevalent chronic disease that affects millions of individuals worldwide, with an increasing prevalence among children. In Oman, asthma is a significant health problem, with a prevalence of 11.5% ... -
Understanding variation in ecology and physiology of marine migratory species.
(Trinity College Dublin. School of Natural Sciences. Discipline of Zoology, 2023)As the world faces the threats of multiple compounded and worsening crises, scientists are racing to gather the knowledge necessary to safeguard entire ecosystems and species. Technological advances are continuously ... -
Adaptive Expression of Forgotten Engrams
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2023)Long-term memories are stored as stable configurations of neuronal ensembles, termed engrams. While investigation of engram cell properties and functionality in memory recall has been extensive, less is known about how ... -
The ebb and flow of Flow: A micro-level investigation of flow experiences as the mechanism underlying energy sustainability and employees' functioning
(Trinity College Dublin. School of Business. Discipline of Business & Administrative Studies, 2023)The present thesis focuses on identifying and examining the psychological mechanism underlying employees? energetic resources at work and while working from home, which has the potential to foster employees? energy ... -
An Investigation into How Line Managers Shape and Influence HR Practice During the Implementation Process
(Trinity College Dublin. School of Business. Discipline of Business & Administrative Studies, 2023)Human resource research has extended beyond the types of practices implemented to how practices are implemented by line managers who hold people management responsibilities (e.g. performance management) to their direct ... -
3D Bioprinting Strategies To Engineer Structurally Organised Meniscal Tissue Grafts
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2023)Lesions to the meniscus are common sports-related injuries that can lead to articular cartilage degeneration and osteoarthritis if left untreated. While surgical repair procedures and meniscal substitutes offer better ... -
The Age-Old Question of ANCA-Associated Vasculitis
(Trinity College Dublin. School of Medicine. Medical Gerontology, 2023)Anti-Neutrophil Cytoplasmic Autoantibody (ANCA)-Associated Vasculitis (AAV) is a group of systemic autoimmune disorders characterised by severe inflammation of the small blood vessels. Unusually for an autoimmune disease, ... -
Non-equilibrium transport properties of quasiperiodic models
(Trinity College Dublin. School of Physics. Discipline of Physics, 2023)The advances in the manipulation of ultracold atoms trapped by optical lattices has established this set-up as a promising analogue simulator of quantum Hamiltonians. The extended coherence times allow for the monitoring ... -
A reliabilist-teleological account of Plato's theory of knowledge based on the Timaeus, the Republic and the Theaetetus
(Trinity College Dublin. School of Social Sciences & Philosophy. Discipline of Philosophy, 2023)Whether, in Plato's epistemology, the Forms can be grasped without using the inferior epistemic capacities, and whether the inferior epistemic capacities contribute to one's grasp of F-ness and the Form F - These are the ... -
An Analysis of the Biopsychosocial Factors including Sex and Pregnancy in Women with Axial Spondyloarthritis; Data from the Ankylosing Spondylitis Registry of Ireland (ASRI)
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2023)With advances in pathophysiology, development of novel classification criteria and the advent of new therapeutic agents the field of axial spondyloarthritis (axSpA) is rapidly evolving. Despite this, the impact and interplay ... -
Frail by four different measures and new adverse events from lower blood pressure control in hypertensive older adults: a 2-year prospective study in The Irish Longitudinal Study on Ageing (TILDA)
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2023)Frail by four different measures and new adverse events from lower blood pressure control in hypertensive older adults: a 2-year prospective study in The Irish Longitudinal Study on Ageing (TILDA) Student: Patrick O?Donoghue ... -
Milking extracellular vesicles for health benefit using a multi-omics approach
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2023)Milk is remarkable source of nutrients (i.e., proteins, fat, and sugars) and extracellular vesicles (EVs). EVs are tiny vesicles release by cells into all biofluids including milk. Milk EVs have been gathered huge attention ...
