Browsing Mechanical, Manufacturing & Biomedical Eng by Sponsor "Science Foundation Ireland (SFI)"
Now showing items 41-60 of 125
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The effect of the VOF-CSF static contact angle boundary condition on the dynamics of sliding and bouncing elliposidal bubbles.
(2011)The staticcontactangle is the only empiricism introduced in a Volume of Fluid?Continuum Surface Force (VOF?CSF) model of bubbly flow. Although it has previously been shown to have a relatively limited effect on the accuracy ... -
Engineering a Corneal Stromal Equivalent Using a Novel Multilayered Fabrication Assembly Technique.
(2020)To overcome the serious shortage of donor corneas for transplantation, alternatives based on tissue engineering need to be developed. Decellularized corneas are one potential alternative, but their densely packed collagen ... -
Engineering of large cartilaginous constructs through the use of microchanneled hydrogels and rotational culture
(2009)The development of functional engineered cartilaginous tissues of sufficient size that can be used clinically to treat large defects remains a major and significant challenge. This study investigated if the introduction ... -
Engineering osteochondral constructs through spatial regulation of endochondral ossification.
(2013)Chondrogenically primed bone marrow derived mesenchymal stem cells (MSCs) have been shown to become hypertrophic and undergo endochondral ossification when implanted in vivo. Modulating this endochondral phenotype may ... -
Expansion in the presence of FGF-2 enhances the functional development of cartilaginous tissues engineered using infrapatellar fat pad derived MSCs
(2012)MSCs from non-cartilaginous knee joint tissues such as the infrapatellar fat pad (IFP) and synovium possess significant chondrogenic potential and provide a readily available and clinically feasible source of chondroprogenitor ... -
Experimental Study of Gas Injected Bubble Growth from Submerged Orifices
(2013)This work investigates the mechanism of adiabatic gasbubblegrowth from submergedorifices with the view of elucidating the interdependence of the bubble shape and the pressure field during growth and departure. Air injection ... -
Experimental Validation of a Computational Fluid Dynamics Methodology for Transitional Flow Heat Transfer Characteristics of a Steady Impinging Jet
(2014)This paper presents a computational fluid dynamics (CFD) methodology to accurately predict the heat transfer characteristics of an unconfined steady impinging air jet in the transitional flow regime, impinging on a planar ... -
Exploring the Applicability of Robot-Assisted UV Disinfection in Radiology
(2021)The importance of infection control procedures in hospital radiology departments has become increasingly apparent in recent months as the impact of COVID-19 has spread across the world. Existing disinfectant procedures ... -
Flow regime characterisation of an impinging axisymmetric synthetic jet
(2013)Impinging synthetic jets have excellent potential for energy-efficient local cooling in confined geometries. For a given geometry, synthetic jet flows are mainly characterised by the Reynolds number and the ratio of stroke ... -
Functional Properties of Cartilaginous Tissues Engineered From Infrapatellar Fat Pad Derived Mesenchymal Stem Cells.
(2010)Articular cartilage has a poor intrinsic capacity for self-repair. The advent of autologous chondrocyte implantation has provided a feasible method to treat cartilage defects. However, the associated drawbacks with the ... -
Fundamental Insights into Arterial Remodelling; Strain-Mediated Degradation of Arterial Collagen
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2019)Maladaptive remodelling of structurally significant collagen fibres in the arterial wall is believed to play a critical role in the development and progression of degenerative arterial disease. A greater understanding of ... -
A general correlation for the stagnation point Nusselt number of an axisymmetric impinging synthetic jet
(2011)Whereas the heat transfer mechanisms in steady impinging jets are well understood, the available knowledge of heat transfer to impinging synthetic jets remains inconsistent. This paper provides an objective comparison of ... -
Harmonization and standardization of nucleus pulposus cell extraction and culture methods
(2023)Background In vitro studies using nucleus pulposus (NP) cells are commonly used to investigate disc cell biology and pathogenesis, or to aid in the development of new therapies. However, lab-to-lab variability jeopardizes ... -
Heat Transfer Enhancement from Bouncing Bubble Dynamics
(2011)Heat transfer enhancement resulting from the effects of two phase flow can play an important role in for convective cooling. Currently, the effect of bubble/surface interactions has received very little attention. To address ... -
High dynamic range whole-field turbulence measurements in impinging synthetic jets for heat transfer applications
(2010)For applications requiring high local heat transfer rates, recent research has shown that impinging synthetic jets perform comparably to continuous jets, yet without needing external mass flow input. In spite of recent ... -
High-resolution hot-film measurement of surface heat flux to an impinging jet
(2011)To investigate the complex coupling between surface heat transfer and local fluid velocity in convective heat transfer, advanced techniques are required to measure the surface heat flux at high spatial and temporal resolution. ... -
Hydrostatic Pressure Regulates the Volume, Aggregation and Chondrogenic Differentiation of Bone Marrow Derived Stromal Cells
(2021)The limited ability of articular cartilage to has motivated the development of tissue engineering strategies that aim to harness the regenerative potential of mesenchymal stem/marrow stromal cells (MSCs). Understanding ... -
Identification of mechanosensitive genes during skeletal development: Alteration of genes associated with cytoskeletal rearrangement and cell signalling pathways
(2014)Background Mechanical stimulation is necessary for regulating correct formation of the skeleton. Here we test the hypothesis that mechanical stimulation of the embryonic skeletal system impacts expression levels of genes ...