Browsing Mechanical, Manufacturing & Biomedical Eng by Title
Now showing items 80-99 of 894
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Battery Charging Considerations in Small Scale Electricity Generation from a Thermoelectric Module
(2014)This project involves the development of a prototype electrical gen erator for delivering and storing small amounts of electricity. Power is generated using the thermoelectric effect. A single ... -
Bilayered extracellular matrix derived scaffolds with anisotropic pore architecture guide tissue organization during osteochondral defect repair
(2022)While some clinical advances in cartilage repair have occurred, osteochondral (OC) defect repair remains a significant challenge, with current scaffold-based approaches failing to recapitulate the complex, hierarchical ... -
Binder evaporation during powder sheet Additive Manufacturing
(2023)Several Additive Manufacturing methods are well established and found access into regular production in multiple sectors. For processing metals, typically wire or powder is used as feedstock. Wire processing is typically used ... -
Bio-inspired Aerodynamic Noise Control: A Bibliographic Review
(2019)It is well-known that many species of owl have the unique ability to fly silently, which can be attributed to their distinctive and special feather adaptations. Inspired by the owls, researchers attempted to reduce the ... -
Biochemical Markers of the Mechanical Quality of Engineered Hyaline Cartilage
(Springer, 2007)The aim of this study was to determine whether or not biochemical markers can be used as surrogate measures for the mechanical quality of tissue engineered cartilage. The biochemical composition of tissue engineered ... -
Biofabrication and bioprinting using cellular aggregates, microtissues and organoids for the engineering of musculoskeletal tissues
(2021)The modest clinical impact of musculoskeletal tissue engineering (TE) can be attributed, at least in part, to a failure to recapitulate the structure, composition and functional properties of the target tissue. This has ... -
Biofabrication of multiscale bone extracellular matrix scaffolds for bone tissue engineering
(2019)Interconnected porosity is critical to the design of regenerative scaffolds, as it permits cell migration, vascularisation and diffusion of nutrients and regulatory molecules inside the scaffold. 3D printing is a promising ... -
Biofabrication of Prevascularised Hypertrophic Cartilage Microtissues for Bone Tissue Engineering
(2021)Bone tissue engineering (TE) has the potential to transform the treatment of challenging musculoskeletal pathologies. To date, clinical translation of many traditional TE strategies has been impaired by poor vascularisation ... -
Biofabrication of spatially organised tissues by directing the growth of cellular spheroids within 3D printed polymeric microchambers
(2019)Successful tissue engineering requires the generation of human scale implants that mimic the structure, composition and mechanical properties of native tissues. Here, we report a novel biofabrication strategy that enables ... -
Biofabrication of vasculature in microphysiological models of bone.
(2021)Bone contains a dense network of blood vessels that are essential to its homoeostasis, endocrine function, mineral metabolism and regenerative functions. In addition, bone vasculature is implicated in a number of prominent ... -
BIOFABRICATION STRATEGIES TO GUIDE THE SELF-ORGANISATION OF BIOMIMETIC CARTILAGE AND OSTEOCHONDRAL TISSUES
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2021)The modest clinical impact of musculoskeletal tissue engineering (TE) can be attributed, at least in part, to a failure to recapitulate the structure, composition and functional properties of the target tissue. This has ... -
Biomaterial based modulation of macrophage polarization: A review and suggested design principles
(2015)Macrophages have long been known for their phagocytic capabilities and immune defence; however, their role in healing is being increasingly recognized in recent years due to their ability to polarize into pro-inflammatory ... -
Biomaterial-based endochondral bone regeneration: A shift from traditional tissue engineering paradigms to developmentally inspired strategies
(2019)There is an urgent, clinical need for an alternative to the use of autologous grafts for the ever increasing number of bone grafting procedures performed annually. Herein, we describe a developmentally inspired approach ... -
A biomechanical analysis of cyclist collisions in Ireland
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2023)As both a mode of transport and recreational activity, cycling has well-known health, environmental, and economic benefits. For these reasons, it has been encouraged in many countries, including the Republic of Ireland. ... -
A Biomechanical and Microstructural Analysis of Bovine and Porcine Pericardium for Use in Bioprosthetic Heart Valves
(2021)Background: Animal-derived pericardium is a key material that enables the successful clinical use of bioprosthetic heart valves. Recently, transcatheter heart valves have placed more emphasis on the enhancement of this ... -
A Biomechanical Assessment of Direct and Inertial Head Loading in Rugby Union
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2018)Rugby union is a territorial, dynamic and high-impact collision sport. Unfortunately, due to its physical and high impact nature, the incidence of concussion is high. There is mounting evidence that repeatedly sustaining ... -
Biomechanical factors in the adaptations of insect tibia cuticle
(2016)Insects are among the most diverse groups of animals on Earth. Their cuticle exoskeletons vary greatly in terms of size and shape, and are subjected to different applied forces during daily activities. We investigated the ... -
Biomechanical origins of osteoporosis
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2004)The contention of this thesis is that a pathological change in bone tissue material properties during osteoporosis ahers the mechanical stimuli to bone remodelling cells and drives them to adapt the trabecular architecture ... -
Biomechanical studies of feline ventral abdominal wall and celiotomy closure techniques.
(2018)Objective: To compare biomechanical properties and mechanism of failure of 3 regions of ventral abdominal wall in cats by using 2 suture materials, 2 suture bite‐to‐stitch intervals (SBSI), and full‐thickness versus ...