On the development of scaffolds for bone tissue engineering
Citation:
Conor Timothy Buckley, 'On the development of scaffolds for bone tissue engineering', [thesis], Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2007, pp 290Download Item:
Abstract:
Many of the current tissue-engineering scaffold-based strategies have suffered from
limited cell depth viability when cultured in vitro, with viable cells existing within
the outer 250-500 μm from the fluid-scaffold interface. This is primarily believed
to be due to the lack of nutrient delivery into and waste removal from the inner
regions of the scaffold construct. Other issues associated with scaffolds involve poor
seeding efficiencies and limited cell penetration resulting in heterogenous cellular
distributions.
Author: Buckley, Conor Timothy
Advisor:
O'Kelly, KevinPublisher:
Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing EngineeringNote:
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