| dc.contributor.advisor | Mills, Kingston | |
| dc.contributor.author | McCann, Chantelle | |
| dc.date.accessioned | 2019-05-01T13:11:48Z | |
| dc.date.available | 2019-05-01T13:11:48Z | |
| dc.date.issued | 2004 | |
| dc.identifier.citation | Chantelle McCann, 'Modulation of immune responses by filamentous haemagglutinin from Bordetella pertussis', [thesis], Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2004, pp 333 | |
| dc.identifier.other | THESIS 7852 | |
| dc.description.abstract | The aim of this study was to investigate the mechanisms by which filamentous haemagglutinin (FHA) from
Bordetella pertussis modulates immune responses. FHA is an adhesion molecule of B. pertussis and
facilitates bacterial binding to the respiratory mucosa following infection. It has been suggested that FHA
modulates Th1 responses by stimulating the production of the immunoregulatory cytokine IL-10 from
macrophages and dendritic cells (DC). IL-10 production by cells of the innate immune system may be
responsible for the delayed development of adaptive immune responses following infection with B.
pertussis. | |
| dc.format | 1 volume | |
| dc.language.iso | en | |
| dc.publisher | Trinity College (Dublin, Ireland). School of Biochemistry and Immunology | |
| dc.relation.isversionof | http://stella.catalogue.tcd.ie/iii/encore/record/C__Rb12398571 | |
| dc.subject | Biochemistry, Ph.D. | |
| dc.subject | Ph.D. Trinity College Dublin | |
| dc.title | Modulation of immune responses by filamentous haemagglutinin from Bordetella pertussis | |
| dc.type | thesis | |
| dc.type.supercollection | thesis_dissertations | |
| dc.type.supercollection | refereed_publications | |
| dc.type.qualificationlevel | Doctoral | |
| dc.type.qualificationname | Doctor of Philosophy (Ph.D.) | |
| dc.rights.ecaccessrights | openAccess | |
| dc.format.extentpagination | pp 333 | |
| dc.description.note | TARA (Trinity's Access to Research Archive) has a robust takedown policy. Please contact us if you have any concerns: rssadmin@tcd.ie | |
| dc.identifier.uri | http://hdl.handle.net/2262/86475 | |
