| dc.contributor.advisor | Lavelle, Ed | |
| dc.contributor.author | Mori, Andres | |
| dc.date.accessioned | 2019-11-13T11:58:57Z | |
| dc.date.available | 2019-11-13T11:58:57Z | |
| dc.date.issued | 2012 | |
| dc.identifier.citation | Andres Mori, 'Chitosan based adjuvants promote proinflammatory Th1 and Th17 responses', [thesis], Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2012, pp 235 | |
| dc.identifier.other | THESIS 9978 | |
| dc.description.abstract | Particulate vaccine adjuvants, including alum and biodegradable polymer microparticles,
are strong activators of antigen-specific humoral immunity. These particulates enhance
NLRP3 inflammasome activation, but they are limited in their ability to promote
proinflammatory T cells responses. For diseases such as TB and malaria, promotion of
strong Th1 responses is a prerequisite for effective vaccines but adjuvants that safely
promote such responses with subunit vaccines are lacking. | |
| dc.format | 1 volume | |
| dc.language.iso | en | |
| dc.publisher | Trinity College (Dublin, Ireland). School of Biochemistry and Immunology | |
| dc.relation.isversionof | http://stella.catalogue.tcd.ie/iii/encore/record/C__Rb15349147 | |
| dc.subject | Biochemistry & Immunology, Ph.D. | |
| dc.subject | Ph.D. Trinity College Dublin. | |
| dc.title | Chitosan based adjuvants promote proinflammatory Th1 and Th17 responses | |
| dc.type | thesis | |
| dc.type.supercollection | thesis_dissertations | |
| dc.type.supercollection | refereed_publications | |
| dc.type.qualificationlevel | Doctoral | |
| dc.type.qualificationname | Doctor of Philosophy (Ph.D.) | |
| dc.rights.ecaccessrights | openAccess | |
| dc.format.extentpagination | pp 235 | |
| dc.description.note | TARA (Trinity’s Access to Research Archive) has a robust takedown policy. Please contact us if you have any concerns: rssadmin@tcd.ie | |
| dc.identifier.uri | http://hdl.handle.net/2262/90417 | |
