Structural and functional studies of a turmour killing protein-fatty acid complex

Sullivan, Louise

dc.contributor.advisor	Brodkorb, André
dc.contributor.advisor	Mok, Ken
dc.contributor.author	Sullivan, Louise
dc.date.accessioned	2019-11-14T14:55:45Z
dc.date.available	2019-11-14T14:55:45Z
dc.date.issued	2013
dc.identifier.citation	Louise Sullivan, 'Structural and functional studies of a turmour killing protein-fatty acid complex', [thesis], Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2013, pp 278
dc.identifier.other	THESIS 10294
dc.description.abstract	HAMLET (Human Alpha-lactalbumin Made LEthal to Tumour cells) is a complex between the milk protein a-lactalbumin (a-LA) and a fatty acid, oleic acid (OA), and displays remarkable properties of selectively killing tumour cell lines while leaving healthy differentiated cells relatively intact. HAMLET and BAMLET (its bovine equivalent) both exhibit toxic activity against a wide range of tumour and bacterial models, both in vitro and in vivo.
dc.format	1 volume
dc.language.iso	en
dc.publisher	Trinity College (Dublin, Ireland). School of Biochemistry and Immunology
dc.relation.isversionof	http://stella.catalogue.tcd.ie/iii/encore/record/C__Rb15652099
dc.subject	Biochemistry & Immunology, Ph.D.
dc.subject	Ph.D. Trinity College Dublin.
dc.title	Structural and functional studies of a turmour killing protein-fatty acid complex
dc.type	thesis
dc.type.supercollection	thesis_dissertations
dc.type.supercollection	refereed_publications
dc.type.qualificationlevel	Doctoral
dc.type.qualificationname	Doctor of Philosophy (Ph.D.)
dc.rights.ecaccessrights	openAccess
dc.format.extentpagination	pp 278
dc.description.note	TARA (Trinity’s Access to Research Archive) has a robust takedown policy. Please contact us if you have any concerns: rssadmin@tcd.ie
dc.identifier.uri	http://hdl.handle.net/2262/90620