Browsing RSS Feeds by Sponsor "Biotechnology and Biological Sciences Research Council"
Now showing items 1-7 of 7
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A dimer of the Toll-like receptor 4 cytoplasmic domain provides a specific scaffold for the recruitment of signalling adaptor proteins
(PLoS, 2007)The Toll-like receptor 4 (TLR4) is a class I transmembrane receptor expressed on the surface of immune system cells. TLR4 is activated by exposure to lipopolysaccharides derived from the outer membrane of Gram negative ... -
Dissociable mechanisms of cognitive control in human prefrontal cortex
(The American Physiological Society, 2007)Intelligent behavior depends on the ability to suppress inappropriate actions and resolve interference between competing responses. Recent clinical and neuroimaging evidence has demonstrated the involvement of prefrontal, ... -
Network analysis of the transcriptional pattern of young and old cells of Escherichia coli during lag phase.
(BioMed Central, 2009)Background The aging process of bacteria in stationary phase is halted if cells are subcultured and enter lag phase and it is then followed by cellular division. Network science has been applied to analyse the transcriptional ... -
Pathogenomic analysis of the common bovine Staphylococcus aureus clone (ET3): emergence of a virulent subtype with potential risk to public health
(University of Chicago Press, 2008)A common clone (ET3) of Staphylococcus aureus is responsible for a large proportion of cases of bovine mastitis and occasionally causes zoonotic infections of humans. In the present study, we report the identification of ... -
Spatial representation of predictive motor learning
(American Physiological Society, 2003)A key feature of skilled motor behavior is the ability of the CNS to predict the consequences of its actions. Such prediction occurs when one hand pulls on an object held in the other hand; the restraining hand generates ... -
TILRR, a novel IL-1RI co-receptor, potentiates MyD88 recruitment to control ras-dependent amplification of NF-?B
(The American Society for Biochemistry and Molecular Biology, 2010)Host defense against infection is induced by Toll-like and interleukin (IL)-1 receptors, and controlled by the transcription factor NF-?B. Our earlier studies have shown that IL-1 activation impacts cytoskeletal structure ... -
The transcriptional programme of Salmonella enterica serovar Typhimurium reveals a key role for tryptophan metabolism in biofilms.
(BioMed Central, 2009)Background Biofilm formation enhances the capacity of pathogenic Salmonella bacteria to survive stresses that are commonly encountered within food processing and during host infection. The persistence of Salmonella within ...