Baseline Mobility is Not Associated with Decline in Cognitive Function in Healthy Community-Dwelling Older Adults: Findings From The Irish Longitudinal Study on Ageing (TILDA)

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2017Access:
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Donoghue, O. and Feeney, J. and O'Leary, N. and Kenny, R.A., Baseline Mobility is Not Associated with Decline in Cognitive Function in Healthy Community-Dwelling Older Adults: Findings From The Irish Longitudinal Study on Ageing (TILDA), American Journal of Geriatric Psychiatry, 2017, 1-11Abstract:
Objectives: Few studies examine the relationship between Timed Up-and-Go (TUG),
a commonly used clinical test, and cognitive decline. This study examines whether
TUG, usual gait speed (UGS), and dual-task gait speed (DTGS) predict decline in global
cognition, executive function, processing speed, memory, and attention with follow-
up of up to 5.9 years. Design: Longitudinal study. Setting: The Irish Longitudinal
Study on Ageing (TILDA), a nationally representative cohort study. Participants:
Community-dwelling adults aged ≥65 years, with Mini-Mental State Examination (MMSE)
score ≥18 and no known history of memory impairment, dementia, Alzheimer’s disease
or Parkinson’s disease were included (N = 2,250). Measurements: Participants com-
pleted mobility tasks during the baseline health assessment and cognitive tasks during
interviews conducted at 2 year intervals (waves 1, 2, and 3) and health assessments
(waves 1 and 3). Linear and Poisson mixed effects regression models were used to
examine longitudinal associations between mobility and each cognitive test, adjust-
ing for sociodemographics and physical and mental health. Results: There was little
evidence of an association between TUG, UGS, or DTGS with decline in cognitive func-
tion after adjusting for confounders. Conclusions: These mobility tasks are not sensitive
predictors of cognitive decline in this high-functioning, community-dwelling sample;
nonetheless, limited decline in cognitive function was observed during follow-up.Further
work with longer follow-up and/or analysis of more specific and comprehensive measures associated with gait is required. (Am J Geriatr Psychiatry 2018; 26:438–448)
Author's Homepage:
http://people.tcd.ie/rkennyhttp://people.tcd.ie/feeneyjo
Author: Kenny, Rose; Feeney, Joanne
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American Journal of Geriatric Psychiatry;Availability:
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http://dx.doi.org/10.1016/j.jagp.2017.11.006Metadata
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