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Recent Submissions
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Asclepiades of Bithynia's Medical Molecular Theory and his Contribution to Evolving Understandings of Mental Illness
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2025)Asclepiades of Bithynia (124 BC-40 BC) was a Greek physician who practiced and taught Greek medicine in Rome in the late second and early first century BC. His unique medical system was strongly influenced by Epicurean ... -
Supporting patients and family caregivers in end-of-life care decision-making from the perspective of healthcare professionals in palliative care
(Trinity College Dublin. School of Medicine. Discipline of Occupational Therapy, 2025)Healthcare professionals in specialist palliative care have a key role in conducting end-of-life care discussions with patients and their family caregivers. However, what enables or restricts healthcare professionals in ... -
The impact of migration on the sexual health of migrant men who have sex with men (MSM) in Dublin, Ireland
(Trinity College (Dublin, Ireland). Centre for Global Health, 2007)Background: With a long history of emigration, Ireland has recently experienced an unprecedented growth of immigration due to rapid economic growth and recent European Union (EU) enlargement. Migrant men who have sex with ... -
The effectiveness of smoking cessation interventions for socio-economically disadvantaged women: a systematic review and meta-analysis
(2022)Introduction: This systematic review and meta-analysis assessed the effectiveness of smoking cessation interven- tions among women smokers in low socio-economic status (SES) groups or women living in disadvantaged areas who ... -
A Feasibility Study of Implantable Loop Recorder Monitoring Capacity in Older Fallers
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2025)INTRODUCTION: Falls are one of the most common causes of injury, prolonged hospitalisation, increased dependency and residential care admission amongst older people. There is a known association between cardiovascular ... -
Improvement in cognitive impairment following a 12-week aerobic exercise intervention in individuals with non-cirrhotic chronic hepatitis C in Journal of Viral Hepatitis
(2021)Cognitive impairment occurs in 30%-50% of patients with non-cirrhotic chronic hepatitis C virus (HCV) infection. Exercise is beneficial in preventing and treating cognitive impairment and cardiometabolic abnormalities in ... -
Effectiveness of a low support, remotely accessible, cognitive remediation training programme for chronic psychosis: cognitive, functional and cortical outcomes from a single blind randomised controlled trial
(2018)Background. Cognitive remediation (CR) training has emerged as a promising approach to improving cognitive deficits in schizophrenia and related psychosis. The limited availability of psychological services for psychosis ... -
Gender-Specific Determinants of Instrumental Activities and Associations With Cognitive Decline in TILDA
(2020)Detecting functional decline is critical in recognizing clinical progression into mild cognitive impairment and dementia as people age. This study aimed to investigate differences in Instrumental Activities of Daily ... -
Self-management interventions for cancer survivors: a systematic review
(2018)Purpose: Many cancer survivors experience problems with persisting symptoms such as pain, fatigue, anxiety and depression post-treatment. Self-management interventions are recommended for cancer patients as they can help ... -
The end of life experience of older adults in Ireland
(The Irish Longitudinal Study on Ageing, Trinity College Dublin, 2017)This is the first TILDA topic report examining the end-of-life experience of older adults in Ireland. Using interviews completed by family members and friends, the report examines how people died (place and cause of ... -
Metabolic reprogramming, malignant transformation and metastasis: Lessons from chronic lymphocytic leukaemia and prostate cancer.
(2025)Metabolic reprogramming is a hallmark of cancer, crucial for malignant transformation and metastasis. Chronic lymphocytic leukaemia (CLL) and prostate cancer exhibit similar metabolic adaptations, particularly in glucose and ... -
The assessment, identification and management of Circadian rest-Activity Rhythm Disorders in patients with advanced Cancer (CARDiC)
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2025)People with cancer may experience restless nights and be less physically active during the daytime. People with cancer may also find that the amount of time they spend being physically active or resting changes a lot between ... -
Seroprevalence, Molecular Epidemiology and Immunological Aspects of Human Herpesvirus 8 in Ireland
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2025)Human herpesvirus 8 (HHV-8) seroprevalence and molecular epidemiology vary both geographically and between sub-populations. Recent work has highlighted the importance of proinflammatory cytokines in the pathogenesis of ... -
Novel 'Test of Disease' Markers in Cervical Pre-cancer
(Trinity College Dublin. School of Medicine. Discipline of Histopathology, 2025)Background: Cervical cancer screening, diagnostics, and prevention are rapidly changing with the introduction of HPV-based screening and HPV vaccination. This thesis aims to address some of the key challenges with (a) HPV ... -
The relationship of medications and hyperparathyroidism to bone mineral density in older adults
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2025)Introduction and Aim Bone mineral density (BMD) is one of the strongest predictors of future fracture risk. As the population ages, understanding the effects of commonly prescribed medications on BMD is increasingly ... -
Balancing purity, pragmatism and partnership in occupational therapy clinical research: trials and tribulations of recruiting for a multisite stroke trial
(2025)Purpose – The REfLECTS trial was a randomised controlled trial (RCT) testing effectiveness of mirror box therapy in upper limb rehabilitation among sub-acute stroke patients. REfLECTS was a large-scale, rigorously planned ... -
SARS-CoV-2 Hospital Epidemiology, Risks, Responses and Viral Dynamics Study
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2025)Background: Healthcare workers (HCW) are at increased risk for SARS-CoV-2 infection compared to the general community. The HERD study hypothesises that host, occupational and social factors influence this infection risk. ... -
Preventing Dementia: The Prevalence of Modifiable Risk Factors in People Attending Ireland's First Brain Health Clinic
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2025)Cognition exists on a spectrum which ranges from normal cognition, subjective memory complaints (SMC), mild cognitive impairment (MCI) and dementia. Dementia prevalence is rising globally, driven largely by changing ...
