Browsing Immunology (Theses and Dissertations) by Subject "Immunology"
Now showing items 1-3 of 3
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Investigating Molluscum Contagiosum Virus Protein MC009 as a Novel Inhibitor of Human Innate Immune Signalling
(Trinity College Dublin. School of Medicine. Discipline of Immunology, 2024)Molluscum contagiosum virus (MCV) is a human-adapted poxvirus that causes mild, raised skin lesions which are highly contagious. The lesions are notable for exerting minimal to no inflammation but can persist for long ... -
Investigating the phenotype and functional roles of human liver-resident natural killer (NK) cells
(Trinity College Dublin. School of Medicine. Discipline of Immunology, 2021)The human liver is an immunologically complex organ populated with distinct resident immune cells including liver-resident CD56bright NK (lrNK) cells which have a distinct CD69+CXCR6+T-betloEomeshi phenotype. These ... -
Understanding the Role of IL-36 Family Cytokines in Paediatric IBD
(Trinity College Dublin. School of Medicine. Discipline of Immunology, 2021)Despite significant therapeutic advances, the global incidence of Inflammatory Bowel Diseases (IBD) continues to rise, with approximately 25% of these cases reported in childhood and adolescence. Aberrant CD4+ TΗ cell ...
