Chemistry (Theses and Dissertations): Recent submissions
Now showing items 281-300 of 435
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Characterisation of n-ferrocenyl alkanethiol self-assembled monolayers
(Trinity College (Dublin, Ireland). School of Chemistry, 2007)The study of self-assembled monolayers and their applications in chemistry and materials science have been of interest since the early 1980's. Due to their stable and dense structure self-assembled monolayers have been ... -
Design and synthesis of DMAP-derived organocatalysts for enantioselective induction
(Trinity College (Dublin, Ireland). School of Chemistry, 2007)The development of small organic molecules capable of mimicking enzymatic action (in an asymmetric catalysis context) is a challenge that is receiving widespread attention in contemporary organic chemistry. Herein we report ... -
Photoresponsive Group 8 polyimines : functional components in self-assembled monolayers
(Trinity College (Dublin, Ireland). School of Chemistry, 2008)Chapter 1 describes the synthesis and characterisation of a series of mixed-ligand Ru(II) and Os(II) polypyridyl complexes; these consist of a tridentate, a bidentate and a monodentate ligand. The monodentate ligand is ... -
Towards novel constrained resorcarene-based platforms
(Trinity College (Dublin, Ireland). School of Chemistry, 2007)This thesis entitled "Towards Novel Constrained Resorcarene-Based Platforms" is divided into seven chapters. In Chapter 1, an introduction to resorcarene chemistry is given and a discussion of the various possible isomers ... -
Development of chiral nanoparticles
(Trinity College (Dublin, Ireland). School of Chemistry, 2008)Symmetry and chirality are common occurrences in the natural world. Chiral compounds are extremely important in chemistry, biology and medicine. Chirality has also been envisaged to play an important role in nanotechnology. ... -
Novel bifunctional organocatalysts for enantioselective synthesis
(Trinity College (Dublin, Ireland). School of Chemistry, 2007)Inspired by the efficiency and selectivity achievable by hydrogen bonding in biological catalysis, the work in this thesis is concerned with the application of these principles to the development of small chiral organic ... -
Computational study of the alpha1-Adrenoceptor subtypes and their ligands
(Trinity College (Dublin, Ireland). School of Chemistry, 2008)Adrenoceptors (AR) belong to the G-protein coupled receptor (GPCR) family. These receptors play an important role in regulating many processes in the body related to the central nervous system, vascular system and many ... -
Studies on novel chiral sulfones
(Trinity College (Dublin, Ireland). School of Chemistry, 2008)The research carried out in the present study focuses mainly on the synthesis of some novel chiral sulfones and the studies of their potential applications as chiral auxiliaries in asymmetric synthesis. This thesis is ... -
Development of new 1D metal based nanomaterials: Synthesis, charaterisation and applications
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2019)The main aim of this project was to develop new 1D metal based nanomaterials and explore their use for potential applications in catalysis. This work involves the synthesis, characterisation, and application of new AuAg ... -
The electroanalytical applications of carbon nanotube-modified electrodes
(Trinity College (Dublin, Ireland). School of Chemistry, 2008)In this study, cyclic voltammetry, potential step chronoamperometry, batch amperometry, hydrodynamic voltammetry and electrochemical impedance spectroscopy were used to investigate the physical and chemical properties of ... -
Synthesis and studies of cyclen based lanthanide complexes for the detection of ions and molecules and the hydrolysis of phosphodiesters
(Trinity College (Dublin, Ireland). School of Chemistry, 2005)This thesis entitled "Cyclen Based Lanthanide Complexes for the Detection of Ions and Molecules and the Hydrolysis of Phosphodiesters" is divided into five chapters. Chapter 1, the introduction, is divided into two parts. ... -
Synthesis of some 8-Aza-7-deazaguanines as potential inactivators of Atase
(Trinity College (Dublin, Ireland). School of Chemistry, 2004)Certain cancer chemotherapeutic agents act by alkylating the O6-position of guanine residues in DNA. This lesion can ultimately cause the death of the targeted cancer cells. However, the efficacy of the cytotoxic effect ... -
N-containing polyaryl ligands in coordination and supramolecular chemistry
(Trinity College (Dublin, Ireland). School of Chemistry, 2007)Part 1 describes the synthetic route and the characterisation of a family of nitrogen heterosuperbenzene compounds. Those polyaromatic ligands, which contain a fused dipyrimidine unit possess unusual photophysical properties ... -
Design, synthesis and photophysical evaluation of novel luminescent sensing devices : from anion sensors to heteroditopic receptors
(Trinity College (Dublin, Ireland). School of Chemistry, 2008)This thesis entitled "Design, Synthesis and Photophysical Evaluation of Novel Luminescent Sensing Devices: From Anion Sensors to Heteroditopic Receptors" is divided into six chapters. Chapter 1, the introduction, is divided ... -
The synthesis, photophysical and biological evaluation of Novel Bis(1,8-naphthalimides)
(Trinity College (Dublin, Ireland). School of Chemistry, 2007)Chapter One provides a review of 1,8-naphthalimide research and, in particular, the exploration of such compounds as anti-cancer agents. Advances in anti-cancer therapeutics and targeting of DNA are also discussed. A ... -
Computational study of the a1A-adrenoceptor and its ligands
(Trinity College (Dublin, Ireland). School of Chemistry, 2005)Adrenoceptors belong to the 'super-family' of seven transmembrane domain receptors known as G protein coupled receptors (GPCRs), which produce their effects through coupling with G proteins. Nine different subtypes of ... -
An electrochemical study of electroactive, ferrocene-terminated, self-assembled monolayers
(Trinity College (Dublin, Ireland). School of Chemistry, 2008)Nanoscience includes the study of objects and systems in which at least one dimension is 1-100 nm. At these sizes, nanosystems can exhibit interesting and useful physical behaviours based on quantum phenomena. An area of ... -
Synthesis and structural analysis of mononuclear to polymeric 2,2'-bipyridyl lanthanide, main group and transition metal complexes
(Trinity College (Dublin, Ireland). School of Chemistry, 2007)The main body of work within this thesis lies within the field of supramolecular chemistry and more specifically concerns the synthesis of coordination complexes involving 2,2'-bipyridyl ligands. A range of coordination ... -
Synthesis and physical evaluation of lanthanide ion based complexes for the hydrolysis of phosphodiesters
(Trinity College (Dublin, Ireland). School of Chemistry, 2006)This thesis describes the synthesis and complexation characteristics of a series of cyclen based lanthanide complexes, designed for hydrolysis of phosphodiesters. Chapter one gives an introduction into the field of ... -
A novel synthesis of Loratadine and studies on Stobbe-like condensation reactions
(Trinity College (Dublin, Ireland). School of Chemistry, 2007)Loratadine is one of the best-selling, non-sedative antihistamines worldwide. Numerous papers have been published in academic and patent literature focussing on improvements or alternatives to the original synthesis of ...
