Browsing Medical Gerontology (Theses and Dissertations) by Subject "ageing"
Now showing items 1-3 of 3
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Cerebral haemodynamics in older adults: Multi-modal studies utilizing near infrared spectroscopy and non-invasive continuous blood pressure monitoring in a large longitudinal cohort
(Trinity College Dublin. School of Medicine. Discipline of Medical Gerontology, School of Medicine, Trinity College Dublin, 2025)Sufficient cerebral blood flow (CBF) is critical for brain health and normal cognitive function, and cerebral hypoperfusion is implicated as a pathway to cognitive decline, as well as other adverse outcomes such as falls, ... -
An evaluation ofthe Allostatic Load framework for quantifying differences inhealth and longevity
(Trinity College Dublin. School of Medicine. Discipline of Medical Gerontology, 2023)The Allostatic Load (AL) framework posits that chronic or repeated exposure to stressors can cause dysregulation of multiple interrelated physiological systems, which if prolonged, may ultimately lead to deteriorations in ... -
Identification of predictors of gait speeds in The Irish Longitudinal Study on Ageing using automated feature selection and explainable machine learning
(Trinity College Dublin. School of Medicine. Discipline of Medical Gerontology, 2023)This work reports the novel application of automated feature selection and explainable machine learning to identify and compare, in participants aged 50 years or over from wave 3 of The Irish Longitudinal Study on Ageing ...