Medical Gerontology (Scholarly Publications): Recent submissions
Now showing items 61-80 of 494
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Critiquing a study or a paradigm?: In response to: The Promise of Allostatic Load Rests Upon Strategic Operationalization, Scoring, and Targeted Interventions.
(2021)We are thankful to Li and Rosemberg for their commentary on our study and for giving us the opportunity to respond. Firstly, it should be acknowledged that we agree with many of the points raised as their commentary reads ... -
Tooth loss and regional grey matter volume.
(2022)Objectives: To investigate whether tooth loss was associated with regional grey matter volume (GMV) in a group of community dwelling older men and women from Ireland. Methods: A group of 380 dementia-free men and women ... -
Unreported urinary incontinence: population-based prevalence and factors associated with non-reporting of symptoms in community-dwelling people ≥ 50 years
(2020)Purpose: Concerns exist around under-detection and under-treatment of urinary incontinence (UI) in specific patient groups, particularly older people. The aim of this study is to ascertain the prevalence of unreported UI ... -
Asymptomatic orthostatic hypotension and risk of falls in community-dwelling older people
(2022)Introduction: Many older people with orthostatic hypotension (OH) may not report typical symptoms of dizziness, light- headedness or unsteadiness. However, the relationships between OH and falls in the absence of typical ... -
Sub-clinical orthostatic hypotension is associated with greater subjective memory impairment in older adults
(2017)Introduction: Orthostatic blood pressure (BP) is a measure of cardiovascular autonomic function. Orthostatic BP dysregulation may lie on the causal pathway to dementia. Subjective memory impairment (SMI) is commonly ... -
Mind versus body: Perceived stress and biological stress are independently related to cognitive decline
(2024)Chronic stress may increase risk of age-related cognitive decline. ‘Stress’, however, is a multidimensional construct and few studies have investigated the inter-relationship of subjective stress and biological stress ... -
Overprescribing among older people near end of life in Ireland: Evidence of prevalence and determinants from The Irish Longitudinal Study on Ageing (TILDA).
(2022)International evidence shows that people approaching end of life (EOL) have high prevalence of polypharmacy, including overprescribing. Overprescribing may have adverse side effects for mental and physical health and ... -
Nutrition is associated with differences in multisensory integration in healthy older adults
(2024)Diet can influence cognitive functioning in older adults and is a modifiable risk factor for cognitive decline. However, it is unknown if an association exists between diet and lower-level processes in the brain underpinning ... -
End-of-life experience for older adults in Ireland: results from the Irish longitudinal study on ageing (TILDA).
(2020)Background: End-of-life experience is a subject of significant policy interest. National longitudinal studies offer valuable opportunities to examine individual-level experiences. Ireland is an international leader in ... -
Religious Attendance, Religious Importance, and the Pathways to Depressive Symptoms in Men and Women Aged 50 and Over Living in Ireland
(2019)Objectives: We aimed to explore the relationship between religiosity and depressive symptoms longitudinally. Method: We used four waves (2009-2016) of the Irish Longitudinal Study on Ageing (TILDA) to create growth curve ... -
Psychotropic medication use and future unexplained and injurious falls and fracture amongst community-dwelling older people: data from TILDA
(2023)Purpose: Psychotropic medications (antidepressants, anticholinergics, benzodiazepines, 'Z'-drugs and antipsychotics) are frequently identified as Falls Risk Increasing Drugs. The aim of this study is to clarify the association ... -
Is orthostatic hypotension and co-existing supine and seated hypertension associated with future falls in community-dwelling older adults? Results from The Irish Longitudinal Study on Ageing (TILDA)
(2021)Orthostatic hypotension (OH) often co-exists with hypertension. As increasing age affects baroreflex sensitivity, it loses its ability to reduce blood pressure when lying down. Therefore, supine hypertension may be an ... -
The association between kidney function, cognitive function, and structural brain abnormalities in community-dwelling individuals aged 50+ is mediated by age and biomarkers of cardiovascular disease.
(2023)Aims: Cognitive impairment has been associated with kidney function and chronic kidney disease. Whether this association is due to accelerated cardiovascular disease (CVD) or an independent specific kidney function effect ... -
White matter fibre density in the brain's inhibitory control network is associated with falling in low activity older adults.
(2024)Recent research has indicated that the relationship between age-related cognitive decline and falling may be mediated by the individual's capacity to quickly cancel or inhibit a motor response. This longitudinal investigation ... -
Is there a bidirectional association between sedentary behaviour and cognitive decline in older adults? Findings from the Irish Longitudinal Study on Ageing
(Elsevier BV, 2021)Research on whether sedentary behaviour (SB) is related to cognitive decline in older individuals is conflicting, potentially caused by methodological differences in previous studies. To inform public health policies, we ... -
Fear of falling: A manifestation of executive dysfunction?
(2019)Objective: Fear of falling (FoF) may be an early marker of decline in global cognitive functioning, but associations with specific domains of cognitive functioning are unclear. The aim was to examine associations between ... -
Predictors of incident malnutrition in older Irish adults from The Irish Longitudinal Study on Ageing (TILDA) cohort- a MaNuEL study.
(2018)Older adults are at increased risk of malnutrition, which is associated with poorer health, quality of life, and worse disease outcomes. This study identifies predictors of incident malnutrition using data from a subsample ... -
Low folate predicts accelerated cognitive decline: 8-year follow-up of 3140 older adults in Ireland
(2022)Objective: To examine associations of plasma folate concentrations and risk of global and domain-specific cognitive decline in older people. Methods: Data of 3140 participants from The Irish Longitudinal Study on Ageing ... -
Plasma concentrations of vitamin B12 and folate and global cognitive function in an older population: cross-sectional findings from The Irish Longitudinal Study on Ageing (TILDA)
(2020)The uncertainty surrounding high intakes of folic acid and associations with cognitive decline in older adults with low vitamin B12 status has been an obstacle to mandatory folic acid fortification for many years. We ... -
The impact of prior exposure to stressful life events and current perceived stress on heart rate variability in older adults: Results from the Irish longitudinal study on ageing.
(2015)Exposure to cumulative stressful life events (LEs) has been shown to have adverse effects on physical and mental well-being. Evidence also suggests that high perceived stress (PS) is associated with poorer health. ...
