Mechanical & Manufacturing Eng (Scholarly Publications): Recent submissions
Now showing items 501-520 of 700
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A validated numerical-experimental design methodology for a movable supersonic ejector compressor for waste-heat recovery
(2013)The aim of this paper is to develop the technical knowledge, especially the optimum geometries, for the design and manufacturing of a supersonic gas-gas ejecto r for a waste heat driven vehicle cooling system. Although ... -
A comparison of self-assembly and hydrogel encapsulation as a means to engineer functional cartilaginous grafts using culture expanded chondrocytes.
(2014)Despite an increased interest in the use of hydrogel encapsulation and cellular self-assembly (often termed "self-aggregating" or "scaffold-free" approaches) for tissue-engineering applications, to the best of our knowledge, ... -
Exploring the roles of integrin binding and cytoskeletal reorganization during mesenchymal stem cell mechanotransduction in soft and stiff hydrogels subjected to dynamic compression.
(2014)The objective of this study was to explore how the response of mesenchymal stem cells (MSCs) to dynamic compression (DC) depends on their pericellular environment and the development of their cytoskeleton. MSCs were first ... -
Infrapatellar Fat Pad-Derived Stem Cells Maintain Their Chondrogenic Capacity in Disease and Can be Used to Engineer Cartilaginous Grafts of Clinically Relevant Dimensions.
(2014)A therapy for regenerating large cartilaginous lesions within the articular surface of osteoarthritic joints remains elusive. While tissue engineering strategies such as matrix-assisted autologous chondrocyte implantation ... -
Substrate stiffness and oxygen availability as regulators of mesenchymal stem cell differentiation within a mechanically loaded bone chamber.
(2014)M echanical stimuli such as tissue deformation and fluid flow are often implicated as regulators of mesenchymal stem cell (MSC) differentiation during regenerative events in vivo . However , in vitro studies ... -
Controlled release of transforming growth factor-?3 from cartilage-extra-cellular-matrix-derived scaffolds to promote chondrogenesis of human-joint-tissue-derived stem cells.
(2014)Abstract: The objective of this study was to develop a scaffold derived from cartilaginous extracellular matrix (ECM) that could be used as a growth factor delivery system to promote chondrogenesis of stem cells. ... -
Engineering cartilage or endochondral bone: A comparison of different naturally derived hydrogels.
(2015)Cartilaginous tissues engineered using mesenchymal stem cells (MSCs) have been shown to generate bone in vivo by executing an endochondral programme. This may hinder the use of MSCs for articular cartilage regeneration, ... -
Optimum Parameters for Freeze-Drying Decellularized Arterial Scaffolds
(2013)Decellularized arterial scaffolds have achieved success in advancing toward clinical use as vascular grafts. However, concerns remain regarding long-term preservation and sterilization of these scaffolds. Freeze drying ... -
An Experimental Study to Determine the Optimal Access Route for Renal Artery Interventions
(2013)Objective The standard approach for endovascular treatment of the renal artery is access via the common femoral artery. However, approximately one in eight patients have a renal artery take-off angle that is less than ... -
Observations of Surface Acoustic Wave Strain and Resistive Strain Measurements on Broaching Tools for Process Monitoring
(2014)The monitoring of high end material removal processes continues to develop to greater levels of technical sophistication which in turn enable greater levels of insight into the process phenomena occurring at the tool-chip ... -
The energy saving opportunity in targeting non-value add manufacturing activities - a structured approach
(2014)With an ongoing increase in industrial energy demand anticipated in Europe, energy efficiency continues to be an important focus within industrial environments. This paper documents an approach to support the study and ... -
Microstructure and Micro Hardness of Friction Stir Welded AA2024-T3 Joints
(2014)Macrostructure, microstructure and micro hardness of friction stir welded AA2024 - T3 joints was studied. The influence of tool pin profile on the microstructure and hardness of these joints was examined. Square, ... -
THE ROLE OF VERIFICATION IN COMPUTER MODELLING: A CASE STUDY IN SOLIDIFICATION PROCESSING
(2014)Computer modelling has become an important aspect of engineering science and technology. Bespoke computer models are routinely under development and are often applied to specific manufacturing and materials processes. ... -
High dynamic range particle image velocimetry applied to heat convection studies
(2014)Convective heat transfer occurs in a wide range of engineering applications, from nuclear reactors to portable electronic devices. Accurate whole-field turbulence and flow measurements are crucial to understanding convective ... -
Bubble Impingement and the Mechanisms of Heat Transfer
(2014)Heat transfer augmentation resulting from the effects of two phase flow can play a significant role in convective cooling applications. To date, the interaction between a rising gas bubble impinging on a heated horizontal ... -
Veins improve fracture toughness of insect wings
(2012)During the lifetime of a flying insect, its wings are subjected to mechanical forces and deformations for millions of cycles. Defects in the micrometre thin membranes or veins may reduce the insect's flight performance. ...
