Browsing Genetics (Theses and Dissertations) by Sponsor "GOIPG/2021/870 Irish Research Council Government of Ireland Postgraduate Scholarship Programme"

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    • Investigating the effects of H3K27M on PRC1 in Diffuse Midline Glioma 

      Lagan, Eimear (Trinity College Dublin. School of Genetics & Microbiology. Discipline of Genetics, 2025)
      Diffuse midline glioma (DMG) is a universally lethal paediatric brain tumour characterised by a mutation in histone H3 (H3K27M). This mutation leads to a global reduction in the repressive histone modification H3K27me3. ...