Browsing Genetics (Scholarly Publications) by Subject "EVOLUTION"
Now showing items 1-5 of 5
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A chromatin-independent role of Polycomb-like 1 to stabilize p53 and promote cellular quiescence.
(2015)Polycomb-like proteins 1-3 (PCL1-3) are substoichiometric components of the Polycomb-repressive complex 2 (PRC2) that are essential for association of the complex with chromatin. However, it remains unclear why three ... -
New genes from non-coding sequence: the role of de novo protein-coding genes in eukaryotic evolutionary innovation
(2015)The origin of novel protein-coding genes de novo was once considered so improbable as to be impossible. In less than a decade, and especially in the last five years, this view has been overturned by extensive evidence from ... -
Protein coadaptation and the design of novel approaches to identify protein-protein interactions
(2011)Proteins rarely function in isolation but they form part of complex networks of interactions with other proteins within or among cells. The importance of a particular protein for cell viability is directly dependent upon ...